Title: Covalent Modification of RNA for In Vitro and In Vivo Delivery. Number: 20040167090. Filed: Feb. 19, 2004. Lead Inventor: Sean Monahan, Mirus.

According to the patent application’s abstract, the invention comprises “post-synthetic modification of RNA for the delivery of the RNA to a mammalian cell. The modifications enhance [resistance] of the RNA to nuclease digestion, and [enhance] delivery of the RNA to the cell whether the RNA is delivered alone or in combination with a transfection agent,” it states.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.