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Sirnaomics Presents Preclinical HPV Data

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Sirnaomics this week released preclinical data showing that two siRNAs against different strains of human papillomavirus could halt growth of papillomas in an animal model of HPV infection.

According to the company, siRNAs against HPV16 and HPV18, formulated with histidine-lysine co-polymer into nanoparticles, were delivered topically to a rabbit skin papilloma model challenged by chimeric human-rabbit papillomavirus and inhibited papilloma growth.

The data were presented this week at the 28th International Papillomavirus conference, and were generated in collaboration with Penn State University researcher Neil Christensen, Sirnaomics said.

The Scan

WHO Seeks Booster Pause

According to CNN, the World Health Organization is calling for a moratorium on administering SARS-CoV-2 vaccine boosters until more of the world has received initial doses.

For Those Long Legs

With its genome sequence and subsequent RNAi analyses, researchers have examined the genes that give long legs to daddy longlegs, New Scientist says.

September Plans

The New York Times reports that the US Food and Drug Administration is aiming for early September for full approval of the Pfizer-BioNTech SARS-CoV-2 vaccine.

Nucleic Acids Research Papers on Targeting DNA Damage Response, TSMiner, VarSAn

In Nucleic Acids Research this week: genetic changes affecting DNA damage response inhibitor response, "time-series miner" approach, and more.