Sirna Initiates Phase I Trial of siRNA-Based Treatment for AMD in Another Sort of First | GenomeWeb

November, it seems, has become the month of firsts for the RNAi sector.

A few weeks ago, Acuity Pharmaceuticals reported that it had begun dosing patients in a phase I study with its siRNA therapy for age-related macular degeneration. This marked the first time an RNAi drug has been used in humans (see RNAi News, 11/12/2004).

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In PLOS this week: genetic study of breast cancer in Egyptian families, mutations linked to cleft lip and palate, and more.

Council Bluffs, Iowa, schools are encouraging more girls to pursue STEM courses, according to the Associated Press.

Because of new open-access requirements, Gates Foundation-funded researchers can't publish in some top journals, Nature News reports.

In Science this week: deletion of one microRNA allows pluripotent stem cells to form embryonic and non-embryonic lineages, and more.