Silence Therapeutics this week announced that German regulators have approved the company's application to begin a phase I study of its siRNA-based cancer drug Atu027.

Atu-027 is a systemically administered drug comprising modified, blunt-ended siRNAs targeting PKN-3, a protein kinase that company researchers have linked to tumor growth and metastases, that have been formulated with a mixture of cationic and fusogenic lipids.

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The Seattle Times writes that pharmacogenomics testing can help choose medications that may work best for people with depression.

Researchers report that deleting one gene from butterflies affects their wing coloration patterns, according to the Washington Post.

In PNAS this week: genome sequencing of weevil symbionts, retinoid X receptor deletion in lung cancer metastasis, and more.

Sequencing could help combat foodborne illnesses, according to a blog post by Food and Drug Administration officials.