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Sigma to Develop, Market Rubicon's RNA-Amplification Tool

NEW YORK (GenomeWeb News) — Sigma-Aldrich will develop and market Rubicon Genomics’ RNA-amplification product, Sigma said today.
 
Rubicon’s Transplex whole transcriptome-amplification tool works from plant, animal, and microorganisms and allows samples to be amplified from between 1,000 and 10,000 fold in a few hours.
 
Sigma said that under the agreement Rubicon will retain all rights to the Transplex for use in its molecular diagnostics ventures.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.