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Sigma-Aldrich, Qiagen, University of Tokyo

Sigma-Aldrich said this week that it has expanded its shRNA gene family sets in lentiviral format to include the Mission TRC shRNA human kinase gene family.

Qiagen has recently introduced the miRNeasy kits, a line of kits that enable purification of total RNA, including miRNA, or enrichment of miRNA and other small RNAs in a separate fraction.
The miRNeasy 96 kit is the first kit available for high-throughput purification in a 96-well format, the company said.
Qiagen also has launched RNA stabilization solutions, which allow samples to be stabilized, processed, stored, and transported at ambient temperature.

Researchers from the University of Tokyo recently launched siVirus, a web-based antiviral siRNA design tool.
The tool searches for functional, off-target minimized siRNAs targeting highly conserved regions of divergent viral sequences, according to the researchers.
The siVirus tool can be found at, and currently covers HIV-1, hepatitis C, SARS, and influenza.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.