NEW YORK (GenomeWeb) — A team of scientists from the Scripps Research Institute this week reported the crystal structure of a microRNA bound to human Argonaute 2 both before and after their engagement with a target mRNA, showing how the protein starts off by exposing only a small portion of its guide RNA as the complex searches for targets.

The research also identified a key aspect of how an miRNA/Ago2 complex uses a metal ion to prevent degradation of a target in the absence of extensive complementarity in favor of repressing its translation.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.

Sep
12
Sponsored by
PerkinElmer

This webinar will cover recent advances in the use of CRISPR for generating animal models and cell lines.