A team of Spanish researchers this week published a new report implicating microRNA-21 in psoriasis and demonstrating that 8-mer locked nucleic acids targeting the miRNA could improve symptoms of the disease in a mouse model.

The findings, the investigators stated, point to the therapeutic potential of miR-21 inhibition, although they caution that the robustness of the approach still needs to be compared with that of existing biologic-based psoriasis drugs.

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