NEW YORK (GenomeWeb) – RXi Pharmaceuticals this week announced the start of a Phase IIa trial of its siRNA-based anti-scarring drug RXI-109 for the prevention of keloid recurrence.

RXI-109 comprises siRNAs designed to inhibit connective tissue growth factor, or CTGF, a protein linked to wound healing and other fibrotic processes. It employs the company's proprietary self-delivering technology, which enables cellular uptake without the need for a delivery vehicle.

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