RXi Awarded NIGMS Grant to Improve Self-Delivering RNAi Agents | GenomeWeb

RXi Pharmaceuticals last month won a six-month grant from the National Institute of General Medical Sciences worth $273,824 to make improvements to its self-delivering RNAi technology.

With the funding, RXi plans to develop a panel of second-generation self-delivering RNAi molecules, called sd-rxRNAs, with “improved potency and pharmacology by incorporating modified nucleotide bases with lipophilic moieties,” according to the grant's abstract.

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