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Rosetta Genomics, Alnylam Pharmaceuticals

USPTO Allows Claims in Two Rosetta miRNA Patent Applications
Rosetta Genomics this week announced that it has received notices of allowance for two US patent applications covering human and viral microRNAs.
The US Patent and Trademark Office typically grants patents on allowed claims within six months after a notice is issued.
According to the company, the first patent application — No. 10/604,726 — is related to two clustered human hairpins and their related miRNAs. The second — No. 10/604,942 — relates to miRNA US5-1, a viral microRNA found in human cytomegalovirus.
“Our leading intellectual property portfolio in microRNAs, which now includes two issued and two allowed patents, is a key component of our business strategy," Rosetta President and CEO Amir Avniel said in a statement. “Combining our proprietary microRNAs with microRNAs discovered in collaboration with Johns Hopkins University [and] exclusively licensed to Rosetta Genomics, we believe we have exclusive access to the majority of known human and viral microRNA genes.”

Japanese Patent Office Allows Claims in Alnylam’s Tuschl II Patent Application
Alnylam Pharmaceuticals said this week that the Japanese patent office has sent the company a notification that it will grant the claims of a patent within the Tuschl II patent family.
The patent application — No. 2002/546670 — includes 39 claims broadly covering compositions, methods, uses, and systems for small interfering RNAs, Alnylam said. The allowed claims specifically include a double-stranded region formed from two RNA strands with a length of 19-23 nucleotides, at least one 3'-overhang at the ends of the double-stranded molecule, and compositions with chemical modifications on the 3'-end of the siRNA to protect against degradation and/or the use of one or more nucleotide modification.
“The grant of claims in the Japanese Tuschl II patent extends the issuance of the Tuschl II patent in the US — US Patent Nos. 7,056,704 and 7,078,196 — and its grant in the European Union —EP 1407044,” the company noted.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.