Arrowhead Research’s top official this week announced that the company has shifted its research and development focus entirely onto RNAi drugs enabled by its dynamic polyconjugate, or DPC, delivery technology.

As part of the change, Arrowhead CEO Christopher Anzalone said that the firm has dropped development of its phase I cancer drug CALAA-01, which had a promising start as the first formulated siRNA drug to enter human testing but faltered in the clinic.

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In PNAS this week: Akt3 amplification in glioma progression, Tibetan Plateau frog genome, and more.

The US Supreme Court has declined to review a decision involving the use of "inadvertently shed" DNA in a police investigation and subsequent conviction.

A panel at the New York Times discusses anonymity and privacy of users of 23andMe's services when access to its database is offered for research.

National Institutes of Health Director Francis Collins appears before a House subcommittee to discuss his agency's budget request.