Despite all the work done during 2003, many working in the RNAi field see more questions than answers in store for 2004.

Delivery to target cells or tissues remains as perhaps the biggest challenge for RNAi researchers, especially those exploring the use of the technology as a therapeutic, and the upcoming year is expected to include a lot of focus on this front.

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The president of France's National Research Agency has resigned, according to Nature News.

A senator wants a "right-to-try" provision in the US Food and Drug Administration funding bill, but an ethicist says at Stat News that it would undermine the role of clinical trials.

In PNAS this week: red algae Porphyra umbicalis genome, deep neural network model for sequencing peptides, and more.

The Guardian's Barbara Ellen has tried out some DNA testing services to see whether they provide valuable information.