For RNAi, 2013 proved to be a year largely marked by incremental successes that, while not always the most attention grabbing, reflect the maturity of the gene-silencing technology and have helped it begin to reignite the interest of big pharma in RNA therapeutics.

It was during the past year that RNAi — indeed, RNA therapeutics in general — "have come of age," Regulus Therapeutics CEO Kleanthis Xanthopoulos told Gene Silencing News. "There is no longer skepticism about whether the … approach works."

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