Regulus Therapeutics, a microRNA drugs joint venture between Isis Pharmaceuticals and Alnylam Pharmaceuticals, said this week that it has been notified that the US Patent and Trademark Office has allowed a patent application within one of the company's patent families.

The patent application, No. 20050261218 and titled "Oligomeric Compounds and Compositions for Use in Modulation [of] Small Non-Coding RNAs," claims methods of inhibiting the liver-specific miRNA miR-122, which has been shown to play a role in hepatitis C virus replication.

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.