Recent RNAi-Related Papers of Note: Oct 28, 2005

Oct 28, 2005

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Recent RNAi-Related Papers of Note
Title	Citations	Authors
Combining RNA Interference and Kinase Inhibitors Against Cell Signalling Components Involved in Cancer	BMC Cancer, Oct.2005; 3: 5, 125	Hanson et al.
Knockdown of c-Met by Adenovirus-Delivered Small Interfering RNA Inhibits Hepatocellular Carcinoma Growth In Vitro and In Vivo	Molecular Cancer Therapeutics, Oct. 2005; 4: 10, 1577-1584	Li et al.
RNA Pol II Subunit Rpb7 Promotes Centromeric Transcription and RNAi-Directed Chromatin Silencing	Genes & Development, Oct. 1, 2005; 19: 19, 2301-2306	Ekwall et al.
Second-Generation shRNA Libraries Covering the Mouse and Human Genomes	Nature Genetics, Oct. 2, 2005; epub ahead of print	Hannon et al.
Probing Tumor Phenotypes Using Stable and Regulated Synthetic microRNA Precursors	Nature Genetics, Oct. 2, 2005; epub ahead of print	Lowe et al.
RNAi Therapeutics: SNALPing siRNAs In Vivo	Gene Therapy, Oct. 6, 2005; epub ahead of print	Rossi
A Bi-Functional siRNA Construct Induces RNA Interference and Also Primes PCR Amplification for its Own Quantification	Nucleic Acids Research, Oct. 7, 2005; 33: 18, e151	Milner et al.
Retraction: Hairpin RNAs and Retrotransposon LTRs Effect RNAi and Chromatin-Based Gene Silencing	Science, Oct. 7, 2005; 310: 5745, 49	Allshire
Retraction: RNA Interference-Directed Chromatin Modification Coupled to RNA Polymerase II Transcription	Nature, Oct. 13, 2005; 437: 7061, 1057	Allshire et al.
RNAi: A Potential Therapy for the Dominantly Inherited Nucleotide Repeat Diseases	Gene Therapy, Oct. 20, 2005; epub ahead of print	Davidson et al.
microPrimer: The Biogenesis and Function of microRNA	Development, Nov. 2005; 132: 21, 4645-4652	Zamore and Du
Double-Stranded RNA Induces Sequence-Specific Antiviral Silencing in Addition to Non-Specific Immunity in a Marine Shrimp: Convergence of RNA Interference and Innate Immunity in the Invertebrate Antiviral Response?	Journal of Virology, Nov. 2005; 79:21, 13561-13571	Warr et al.
Dicer-Dependent Turnover of Intergenic Transcripts from the Human Beta-Globin Gene Cluster	Molecular and Cellular Biology, Nov. 2005; 25: 21, 9724-9733	Proudfoot and Haussecker

Filed under

Gene Editing, Gene Silencing, & CRISPR

RNAi

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.