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Recent RNAi-Related Papers of Note: Jul 8, 2005

Recent RNAi-Related Deals of Note
Dissecting RNA Interference Pathway with Small Molecules

Chemistry & Biology,
June 2005; 12: 6, 643-648

Rana et al.
Plant Virus-Derived Small Interfering RNAs Originate Predominantly from Highly Structured Single-Stranded RNAs Journal of Virology,
June 2005; 79: 12, 7812-7818
Burgyan et al.
A Virus-Encoded Inhibitor That Blocks RNA Interference in Mammalian Cells Journal of Virology,
June 2005; 79: 12, 7371-7379
Sullivan and Ganem
Cell Microarrays and RNA Interference Chip Away at Gene Function Nature Genetics,
June 2005; s25-s30
Sabatini et al.
Human Mitochondrial tRNAMet is Exported to the Cytoplasm and Associates with the Argonaute 2 Protein RNA,
June 2005; 11: 6, 849-852
Maniataki and Mourelatos
Sequence Characteristics of Functional siRNAs RNA,
June 2005; 11: 6, 864-872
Rothman et al.
Mammalian microRNAs Derived from Genomic Repeats Trends in Genetics,
June 2005; 21: 6, 322-326
Smalheiser and Torvik
Natural Antisense Transcripts with Coding Capacity in Arabidopsis May Have a Regulatory Role That is Not Linked to Double-Stranded RNA Degradation Genome Biology,
June 1, 2005; epub
Meyer et al.
Efficient Processing of Primary microRNA Hairpins by Drosha Requires Flanking Non-Structured RNA Sequences Journal of Biological Chemistry,
June 1, 2005; epub ahead of print
Zeng and Cullen
Reversal of MDR1 Gene-Dependent Multi-Drug Resistance Using Short Hairpin RNA Expression Vectors Chinese Medical Journal,
June 5, 2005; 118: 11, 893-902
Zheng et al.
MicroRNA-Dependent Localization of Targeted mRNAs to Mammalian P-Bodies Nature Cell Biology,
June 5, 2005; epub ahead of print
Parker et al.
RNA Interference Induced by siRNAs Modified with 4'-Thioribonucleosides in Cultured Mammalian Cells FEBS Letters,
June 6, 2005; 579: 14, 3115-3118
Matsuda et al.
RNA Interference by Mixtures of siRNAs Prepared Using Custom Oligonucleotide Arrays Nucleic Acids Research,
June 7, 2005; 33: 10, e92
Gray et al.
MicroRNA Expression Profiles Classify Human Cancers Nature,
June 9, 2005;
435: 7043, 834-838
Golub et al.
c-Myc-Regulated microRNAs Modulate E2F1 Expression Nature,
June 9, 2005;
435: 7043, 839-843
Mendell et al.
Small Hairpin RNAs Efficiently Inhibit Hepatitis C IRES-Mediated Gene Expression in Human Tissue Culture Cells and a Mouse Model Molecular Therapy,
June 10, 2005;
epub ahead of print
Kaspar et al.
Fruit-Specific RNAi-Mediated Suppression of DET1 Enhances Carotenoid and Flavonoid Content in Tomatoes Nature Biotechnology,
June 12, 2005;
epub ahead of print
Bowler et al.
RNA Interference During Spermatogenesis in Mice Developmental Biology,
June 15, 2005; 282: 2, 524-534
Nakatsuji et al.
Inhibition of Hepatitis C Virus Translation and Subgenomic Replication by siRNAs Directed Against Highly Conserved HCV Sequence and Cellular HCV Cofactors Journal of Hepatology,
June 16, 2005; epub ahead of print
Kruger et al.
Stem Cell Division is Regulated by the microRNA Pathway Nature,
June 16, 2005; 435: 7044, 974-978
Ruohola-Baker et al.
RNA Interference-Directed Chromatin Modification Coupled to RNA Polymerase II Transcription Nature,
June 19, 2005; epub ahead of print
Allshire et al.
Identification of Hundreds of Conserved and Non-Conserved Human microRNAs Nature Genetics,
June 19, 2005; epub ahead of print
Bentwich et al.
Identification of Human Fetal Liver miRNAs by a Novel Method FEBS Letters,
June 21, 2005; epub ahead of print
Zheng et al.
MicroRNAs in Vertebrate Development Current Opinion in Genetics
& Development
June 22, 2005;
epub ahead of print
Efficient Inhibition of Human Telomerase Reverse Transcriptase Expression by RNA Interference Sensitizes Cancer Cells to Ionizing Radiation and Chemotherapy Human Gene Therapy,
June 22, 2005;
epub ahead of print
Inoue et al.
TRBP Recruits the Dicer Complex to Ago2 for microRNA Processing and Gene Silencing Nature,
June 22, 2005;
epub ahead of print
Sheikhatter et al.
RNA Interference and Heterochromatin in the Fission Yeast Schizosaccharomyces pombe Trends in Genetics,
June 22, 2005;
epub ahead of print
Goto et al.
A Fast, Simple Method for Screening Radiation Susceptibility Genes by RNA Interference Biochemical and Biophysical Research Communications,
June 23, 2005; 333: 4, 1370-1377
Harada et al.
Small Interfering RNA Effectively Inhibits Protein Expression and Negative Strand RNA Synthesis from Full-Length Hepatitis C Virus Clone Journal of Medial Virology,
June 23, 2005; 76: 4, 511-519
Dash et al.
Comprehensive Analysis of Heterochromatin- and RNAi-Mediated Epigenetic Control of the Fission Yeast Genome Nature Genetics,
June 24, 2005; epub ahead of print
Grewal et al.
Actively Replicating West Nile Virus is Resistant to Cytoplasmic Delivery of siRNA Virology Journal,
June 28, 2005;
epub ahead of print
Diamond et al.
Dicer-1 and RD31-L Catalyze microRNA Maturation in Drosophila Genes & Development,
June 28, 2005;
epub ahead of print
Liu et al.
Positional Effects of Chemical Modifications on Short Interference RNA Activity in Mammalian Cells Journal of Medicinal Chemistry,
June 30, 2005; 48: 13, 4247-4253
Bhat et al.
The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.