Quark Pharmaceuticals last week unveiled preclinical data demonstrating that its siRNA-based wet age-related macular degeneration and diabetic macular edema therapy, dubbed PF-4523655 and currently under phase II development by partner Pfizer, does not stimulate an immune response that has been associated with similar drugs.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

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