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Products & Services: Mar 5, 2009


GeneCopoeia has recently launched a collection of microRNA functional analysis reagents and tools.

These include miExpress vector-based precursor miRNA-expression clones, which cover all known human, mouse, and rat miRNAs; miTarget miRNA target sequence-expression clones, which cover genome-wide human, mouse and rat genes; and the All-in-One miRNA RT-qPCR system, which consists of a reverse transcription kit, a SYBR green RT-qPCR master mix kit, and a complete set of validated primers for human, mouse, and rat miRNAs.

Sigma-Aldrich has introduced the Mission LentiPlex pooled human and murine shRNA libraries.

These collections include a U6 promoter for shRNA expression in a wide variety of cell lines including embryonic stem cells, the company noted.

Promega has introduced the pmirGlo dual-luciferase miRNA target-expression vector, which the company said allows a luciferase reporter gene assay to measure the function of endogenous or exogenous miRNAs.

"This vector also enables functional studies of sequence variations found in 3'-untranslated regions of genes often related to miRNA binding sites or other modulators of transcript stability," Promega noted.

The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.