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Products & Services: Mar 5, 2009


GeneCopoeia has recently launched a collection of microRNA functional analysis reagents and tools.

These include miExpress vector-based precursor miRNA-expression clones, which cover all known human, mouse, and rat miRNAs; miTarget miRNA target sequence-expression clones, which cover genome-wide human, mouse and rat genes; and the All-in-One miRNA RT-qPCR system, which consists of a reverse transcription kit, a SYBR green RT-qPCR master mix kit, and a complete set of validated primers for human, mouse, and rat miRNAs.

Sigma-Aldrich has introduced the Mission LentiPlex pooled human and murine shRNA libraries.

These collections include a U6 promoter for shRNA expression in a wide variety of cell lines including embryonic stem cells, the company noted.

Promega has introduced the pmirGlo dual-luciferase miRNA target-expression vector, which the company said allows a luciferase reporter gene assay to measure the function of endogenous or exogenous miRNAs.

"This vector also enables functional studies of sequence variations found in 3'-untranslated regions of genes often related to miRNA binding sites or other modulators of transcript stability," Promega noted.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.