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Products & Services: Apr 30, 2009

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Bioo Scientific has introduced the MaxSuppressor In Vivo RNA-Lancer II delivery reagent.

According to the company, the reagent can be used to deliver siRNAs, microRNAs, long double-stranded RNAs, and other RNAi molecules into living animals.


Sigma-Aldrich has released Mission esiRNA, a line of pooled siRNAs against single gene targets.

By targeting each gene target with a pool of hundreds of siRNAs, "the trial-and-error approach of identifying a useful single siRNA is eliminated," the company said. "In addition, the approach should ensure minimal risk of off-target effects and enables the use of one assay per gene."

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.