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Private RNAi, miRNA Tech Firms Find VC Backers in 2008 Despite Financial Turmoil

Despite troubles on Wall Street hammering most publicly traded RNAi and microRNA companies (see related story, this issue) some private firms looking to commercialize drugs based on the technologies have managed to find interested venture-capital investors.
Since the beginning of 2008, privately held companies in the space collectively raised more than $78 million in venture and other private capital.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.