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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Aug 2, 2012

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7-Substituted 8-Aza-7-Deazaadenosines for Modification of the siRNA Major Groove

Organic & Biomolecular Chemistry, July 5, 2012; epub ahead of print
Beal et al.


In Vitro-In Vivo Translation of Lipid Nanoparticles for Hepatocellular siRNA Delivery

ACS Nano, July 6, 2012; epub ahead of print
Anderson et al.


Topical Delivery of siRNA-Based Spherical Nucleic Acid Nanoparticle Conjugates for Gene Regulation

Proceedings of the National Academy of Sciences, July 6, 2012; epub ahead of print
Paller et al.


Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain

Current Biology, July 10, 2012; epub ahead of print
Kay et al.


5' Triphosphate-siRNA: Potent Inhibition of Influenza A Virus Infection by Gene Silencing and RIG-I Activation

Journal of Virology, July 11, 2012; epub ahead of print
Zhou et al.


miRNA-Like Duplexes as RNAi Triggers with Improved Specificity

Frontiers in Non-Coding RNA, July, 12, 2012; epub ahead of print
Tomari et al.


LNA-Mediated Anti-microRNA-155 Silencing in Low-Grade B Cell Lymphoma

Blood, July 13, 2012; epub ahead of print
Ghobrial et al.


A Nuclear Argonaute Promotes Multi-Generational Epigenetic Inheritance and Germline Immortality

Nature, July 18, 2012; epub ahead of print
Kennedy et al.


Right- and Left-Loop Short shRNAs Have Distinct and Unusual Mechanisms of Gene Silencing

Nucleic Acids Research, July 18, 2012; epub ahead of print
Johnston et al.


Deep Sequencing of RNA from Immune Cell-Derived Vesicles Uncovers the Selective Incorporation of Small Non-Coding RNA Biotypes with Potential Regulatory Functions

Nucleic Acids Research, July 19, 2012; epub ahead of print
't Hoen et al.


A Novel Vector-Based Method for Exclusive Over-Expression of Star-Form microRNAs

PLoS One, July 19, 2012; epub ahead of print
Shen et al.


piRNAs and siRNAs Collaborate in Caenorhabditis elegansGenome Defense

Genome Biology, July 20, 2012; epub ahead of print
Kim et al.


Influenza Virus A Infection of Human Respiratory Cells Induces Primary microRNA Expression

Journal of Biological Chemistry, July 20, 2012; epub ahead of print
Horvath et al.


Induction of Alloimmune Tolerance in Heart Transplantation through Gene Silencing of TLR Adaptors

American Journal of Transplantation, July 23, 2012; epub ahead of print
Min et al.


Essential Metabolic, Anti-Inflammatory, and Anti-Tumorigenic Functions of miR-122 in Liver

Journal of Clinical Investigation, July 23, 2012; epub ahead of print
Ghoshal et al.


microRNA-122 Plays a Critical Role in Liver Homeostasis and Hepatocarcinogenesis

Journal of Clinical Investigation, July 23, 2012; epub ahead of print
Tsou et al.


In Vivo Site-Specific Transfection of Naked Plasmid DNA and siRNAs in Mice by Using a Tissue Suction Device

PLoS One, July 23, 2012; epub ahead of print
Konishi et al.


Prospective Study on Circulating microRNAs and Risk of Myocardial Infarction

Journal of the American College of Cardiology, July 24, 2012; 60: 4, 290-299
Mayr et al.


Differential Susceptibility of Human Primary Aortic and Coronary Artery Vascular Cells to RNA Interference

Biochemical and Biophysical Research Communications, July 25, 2012; epub ahead of print
Logerfo et al.


microRNAs Associated with the Different Human Argonaute Proteins

Nucleic Acids Research, July, 25, 2012; epub ahead of print
Meister et al.


The Over-Expression of miR-34a Fails to Block DoHH2 Lymphoma Cell Proliferation by Reducing p53 Via c-MYC Down-Regulation

Nucleic Acid Therapeutics, July 25, 2012; epub ahead of print
Rainaldi et al.


Effective Systemic Delivery of siRNA by Using High-Density Lipoprotein-Mimicking Peptide Lipid Nanoparticles

Nanomedicine, July 26, 2012; epub ahead of print
Zheng et al.


Intact p53-Dependent Responses in miR-34-Deficient Mice

PLoS Genetics, July 26, 2012; epub ahead of print
Ventura et al.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.