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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Jul 5, 2012

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Thermodynamic Control of Small RNA-Mediated Gene Silencing

Frontiers in Non-Coding RNA, June 4, 2012; epub ahead of print
Nagasawa et al.


Nanosized Multi-Functional Polyplexes for Receptor-Mediated siRNA Delivery

ACS Nano, June 7, 2012; epub ahead of print
Wagner et al.


Circulating microRNAs are not Eliminated by Hemodialysis

PLoS One, June 8, 2012; epub ahead of print
Thum et al.


Nanoparticle-Based Therapy in an In Vivo microRNA-155-Dependent Mouse Model of Lymphoma

Proceedings of the National Academy of Sciences, June 8, 2012; epub ahead of print
Slack et al.


siRNA-Design Software for a Target Gene-Specific RNA Interference

Frontiers in Non-Coding RNA, June 11, 2012; epub ahead of print
Naito & Ui-Tei


Solid Formulation of Cell-Penetrating Peptide Nanocomplexes with siRNA and Their Stability in Simulated Gastric Conditions

Journal of Controlled Release, June 12, 2012; epub ahead of print
Langel et al.


Function, Targets, and Evolution of Caenorhabditis elegans piRNAs

Science, June 14, 2012; epub ahead of print
Miska et al.


MUT-16 Promotes Formation of Perinuclear Mutator Foci Required for RNA Silencing in the C. elegans Germline

Genes & Development, June 19, 2012; epub ahead of print
Ruvkun et al.


Coordinated Activities of Human Dicer Domains in Regulatory RNA Processing

Journal of Molecular Biology, June 19, 2012; epub ahead of print
Doudna et al.


piRNAs Initiate an Epigenetic Memory of Nonself RNA in the C. elegans Germline

Cell, June 23, 2012; epub ahead of print
Mello et al.


piRNAs Can Trigger a Multi-Generational Epigenetic Memory in the Germline of C. elegans

Cell, June 23, 2012; epub ahead of print
Miska et al.


microRNAs in Cerebrospinal Fluid as Biomarker for Disease Course Monitoring in Primary Central Nervous System Lymphoma

Journal of Neuro-Oncology, June 23, 2012; epub ahead of print
Schroers et al.


Safe, Long-Term Hepatic Expression of Anti-HCV shRNA in a Non-Human Primate Model

Molecular Therapy, June 26, 2012; epub ahead of print
Corbau et al.


Classification of the Four Main Types of Lung Cancer Using a microRNA-Based Diagnostic Assay

Journal of Molecular Diagnostics, June 27, 2012; epub ahead of print
Aharonov et al.


RNA Interference-Mediated Gene Knockdown within Specific Cell Types

Plant Molecular Biology, June 28, 2012; epub ahead of print
Zhang & Galbraith

The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.