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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: May 3, 2012

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Heterochromatin Protein 1 Homologue Swi6 Acts in Concert with Ers1 to Regulate RNAi-Directed Heterchromatin Assembly

Proceedings of the National Academy of Sciences, April 2, 2012; epub ahead of print
Nakayama et al.


Drosophila Argonaute-1 is Critical for Transcriptional Co-Suppression and Heterochromatin Formation

Chromosome Research, April 3, 2012; epub ahead of print
Bhadra et al.


BRCA1 Regulates microRNA Bigenesis via the Drosha Microprocessor Complex

Journal of Cell Biology, April 9, 2012; epub ahead of print
Kawai & Amano


Extensive Terminal and Asymmetric Processing of Small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs

Nucleic Acids Research, April 9, 2012; epub ahead of print
John et al.


Preparation and Characterization of the Extracellular Domain of Human Sid-1

PLoS One, April 11, 2012; epub ahead of print
Macrae et al.


microRNA Dysregulation in the Spinal Cord Following Traumatic Injury

PLoS One, April 12, 2012; epub ahead of print
Maza et al.


Role of microRNAs in Controlling Gene Expression in Different Segments of the Human Epididymis

PLoS One, April 12, 2012; epub ahead of print
Sullivan et al.


Argonaute Identity Defines the Length of Mature Mammalian microRNAs

Nucleic Acids Research, April 13, 2012; epub ahead of print
Makeyev et al.


miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay

Science, April 13, 2012; 336: 6078, 237-240
Green et al.


The RDE-10/RDE-11 Complex Triggers RNAi-Induced mRNA Degradation by Association with Target mRNA in C. elegans

Genes & Development, April 15, 2012; 26: 8, 846-856
Mak et al.


A Single-Cloning-Step Procedure for the Generation of RNAi Plasmids Producing Long Stem-Loop RNA

Molecular and Biochemical Parasitology, April 20, 2012; epub ahead of print
Kolev et al.


Systemic Delivery of Transthyretin siRNA Mediated by Lactosylated Dendrimer/Alpha-Cyclodextrin Conjugates into Hepatocyte for Familial Amyloidotic Polyneuropathy Therapy

Amyloid, April 21, 2012; epub ahead of print
Arima et al.


Lipid-Conjugates 27-Nucleotide Double-Stranded RNAs with Dicer-Substrate Potency Enhance RNAi-Mediated Gene Silencing

Molecular Pharmaceutics, April 24, 2012; epub ahead of print
Seyama et al.


Single-Cell Analysis of Population Context Advances RNAi Screening at Multiple Levels

Molecular Systems Biology, April 24, 2012; 8: 579
Pelkmans et al.


The Caenorhabditis elegans RDE-10/RDE-11 Complex Regulates RNAi by Promoting Secondary siRNA Amplification

Current Biology, April 26, 2012; epub ahead of print
Ruvkun et al.


Development of [an] siRNA and shRNA Screening System Based on a Kinase Fusion Protein

RNA, April 26, 2012; epub ahead of print
Cools et al.


Reduced Expression of Ribosomal Proteins Relieves microRNA-Mediated Repression

Molecular Cell, April 27, 2012; 46: 2, 171-186
Novina et al.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.