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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Feb 14, 2013

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The 5' Binding MID Domain of Human Argonaute 2 Tolerates Chemically Modified Nucleotide Analogues

Nucleic Acid Therapeutics, Jan. 5, 2013; epub ahead of print
Damha et al.


Therapeutic Effects of microRNA-582-5p and -3p on the Inhibition of Bladder Cancer Progression

Molecular Therapy, Jan. 8, 2013; epub ahead of print
Ochiya et al.


pH-Triggered Nanoparticle-Mediated Delivery of siRNA to Liver Cells In Vitro and In Vivo

Bioconjugate Chemistry, Jan. 10, 2013; epub ahead of print
Miller et al.


An Analysis and Validation Pipeline for Large-Scale RNAi-Based Screens

Scientific Reports, Jan. 16, 2013; epub ahead of print
Church et al.


Derepression of a Neuronal Inhibitor Due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion

Cell, Jan. 17, 2013; 152: 262-275
Gogos et al.


Rat miR-155 Generated from the lncRNA Bic is 'Hidden' in the Alternate Genomic Assembly and Reveals the Existence of Novel Mammalian miRNAs and Clusters

RNA, Jan. 17, 2013; epub ahead of print
Masotti et al.


Deep Sequencing of Small RNAs Identifies Canonical and Non-Canonical miRNA and Endogenous siRNAs in Mammalian Somatic Tissues

Nucleic Acids Research, Jan. 15, 2013; epub ahead of print
Castellano & Stebbing


Inactivation of the microRNA-183/96/182 Cluster Results in Syndromic Retinal Degeneration

Proceedings of the National Academy of Sciences, Jan. 22, 2013; epub ahead of print
Xu et al.


Identification of microRNAs in Calcisponges: Independent Evolution of microRNAs in Basal Metazoans

Journal of Experimental Zoology, Jan. 24, 2013; epub ahead of print
Peterson et al.


On Measuring miRNAs after Transient Transfection of Mimics or Antisense Inhibitors

PLoS One, Jan. 24, 2013; epub ahead of print
Goodall et al.


GATA3 Suppresses Metastasis and Modulates the Tumor Microenvironment by Regulating microRNA-29b Expression

Nature Cell Biology, Jan. 27, 2013; epub ahead of print
Werb et al.


First-in-Man Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

Cancer Discovery, Jan. 28, 2013; epub ahead of print
Burris et al.


Neutral Polymeric Micelles for RNA Delivery

Bioconjugate Chemistry, Jan. 29, 2013; epub ahead of print
Stayton et al.


Surface Modified HK:siRNA Nanoplexes with Enhanced Pharmacokinetics and Tumor Growth Inhibition

Biomacromolecules, Jan. 29, 2013; epub ahead of print
Mixson et al.


Structural Insights into RISC Assembly Facilitated by dsRNA-Binding Domains of Human RNA Helicase A

Nucleic Acids Research, Jan. 29, 2013; epub ahead of print
Fu & Yuan et al.


High-Throughput Sequencing Reveals Extraordinary Fluidity of miRNA, piRNA, and siRNA Pathways in Nematodes

Genome Research, Jan. 30, 2013; epub ahead of print
Ruvkun et al.


Tsw Gene-Based Resistance is Triggered by a Functional RNA Silencing Suppressor Protein of the Tomato Spotted Wilt Virus

Molecular Plant Pathology, Jan. 30, 2013; epub ahead of print
Kormelink et al.


Single-Cell microRNA Analysis Using Microfluidic Flow Cytometry

PloS One, Jan. 30, 2013; epub ahead of print
Singh et al.


Identification of Small RNA Pathway Genes Using Patterns of Phylogenic Conservation and Divergence

Nature, Jan. 31, 2013; epub ahead of print
Ruvkun et al.

The Scan

US Supports Patent Waivers

NPR reports that the Biden Administration has announced its support for waiving intellectual property protections for SARS-CoV-2 vaccines.

Vaccines Versus Variants

Two studies find the Pfizer-BioNTech SARS-CoV-2 vaccine to be effective against viral variants, and Moderna reports on booster shots to combat variants.

CRISPR for What Ails You

The Wall Street Journal writes that CRISPR-based therapies could someday be used to treat common conditions like heart attacks.

Nature Papers Review Integration of Single-Cell Assay Data, Present Approach to Detect Rare Variants

In Nature this week: review of ways to integrate data from single-cell assays, and more.