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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Jan 17, 2013

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Automated Parallel Synthesis of 5'-Triphosphate Oligonucleotides and Preparation of Chemically Modified 5'-Triphosphate Small Interfering RNAs

Bioorganic & Medicinal Chemistry, Dec. 3, 2012; epub ahead of print
Manoharan et al.


microRNA 3' End Nucleotide Modification Patterns and Arm Selection Preference in Liver Tissues

BMC Systems Biology, Dec. 12, 2012; epub ahead of print
Li et al.


A Simple One-Step Method for Producing dsRNA from E. Coli to Inhibit Shrimp Virus Replication

Journal of Virological Methods, Dec. 12, 2012; epub ahead of print
Panyim et al.


microRNA-Centric Measurement Improves Functional Enrichment Analysis of Co-Expressed and Differentially Expression microRNA Clusters

BMC Genomics, Dec. 13, 2012; epub ahead of print
Kim et al.


Preferential Regulation of Stably Expressed Genes in the Human Genome Suggests a Widespread Expression Buffering Role of microRNAs

BMC Genomics, Dec. 13, 2012; epub ahead of print
Zhong et al.


The Role of Human Dicer-dsRBD in Processing Small Regulatory RNAs

PLoS One, Dec. 13, 2012; epub ahead of print
Showalter et al.


Urinary microRNA-10a and microRNA-30d Serve as Novel, Sensitive, and Specific Biomarkers for Kidney Injury

PLoS One, Dec. 13, 2012; epub ahead of print
Zen et al.


Improved Nucleic Acid Descriptors for siRNA Efficacy Prediction

Nucleic Acids Research, Dec. 14, 2012; epub ahead of print
Stanton et al.


Competing and Non-Competing Activities of miR-122 and the 5' Exonuclease Xrn1 in Regulation of Hepatitis C Virus Replication

Proceedings of the National Academy of Sciences, Dec. 17, 2012; epub ahead of print
Lemon et al.


Regulation of Neonatal and Adult Mammalian Heart Regeneration by the miR-15 Family

Proceedings of the National Academy of Sciences, Dec. 17, 2012; epub ahead of print
Sadek et al.


Long-Lived microRNA-Argonaute Complexes in Quiescent Cells can be Activated to Regulate Mitogenic Responses

Proceedings of the National Academy of Sciences, Dec. 17, 2012; epub ahead of print
Thompson et al.


Potent microRNA Suppression by RNA Pol II-Transcribed 'Tough Decoy' Inhibitors

RNA, Dec. 18, 2012; epub ahead of print
Mikkelsen et al.


Rapid and Specific Purification of Argonaute-Small RNA Complexes from Crude Cell Lysates

RNA, Dec. 18, 2012; epub ahead of print
Zamore et al.


Stability of miRNA 5' Terminal and Seed Regions is Correlated with Experimentally Observed miRNA-Mediated Silencing Efficacy

Scientific Reports, Dec. 18, 2012; epub ahead of print
Ui-Tei et al.


siRNA Sequence Model: Re-Design Algorithm Based on Available Genome-Wide Libraries

Journal of Biomolecular Structure and Dynamics, Dec. 20, 2012; epub ahead of print
Kozak


Identification and Functional Demonstration of miRNAs in the Fungus Cryptococcus neoformans

PLoS One, Dec. 26, 2012; epub ahead of print
Zhu et al.


Circularized Synthetic Oligodeoxynucleotides Serve as Promoterless RNA Polymerase III Templates for Small RNA Generation in Human Cells

Nucleic Acids Research, Dec. 28, 2012; epub ahead of print
Ryan et al.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.