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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Dec 6, 2012

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Protection from Feed-Forward Amplification in an Amplified RNAi Mechanism

Cell, Nov. 9, 2012; 151: 4, 885-899
Fire et al.


The Loop Position of shRNAs and Pre-miRNAs is Critical for the Accuracy of Dicer Processing In Vivo

Cell, Nov. 9, 2012; 151: 4, 900-911
Kay et al.


Selective Autophagy Degraded Dicer and Ago2, and Regulates miRNA Activity

Nature Cell Biology, Nov. 11, 2012; epub ahead of print
Vionnet et al.


Dendrimeric Bowties Featuring Hemisphere-Selective Decoration of Ligands for microRNA-Based Therapy

Biomacromolecules, Nov. 12, 2012; epub ahead of print
Luo et al.


Whole-Genome microRNA Screening Identifies Let-7 and miR-18 as Regulators of Germ Layer Formation During Early Embryogenesis

Genes & Development, Nov. 14, 2012; epub ahead of print
Mercola et al.


Conjugating Phosphospermines to siRNAs for Improved Stability in Serum, Intracellular Delivery, and RNAi-Mediated Gene Silencing

Molecular Pharmaceutics, Nov. 14, 2012; epub ahead of print
Lenne-Samuel et al.


RNAi Triggered by Specialized Machinery Silences Developmental Genes and Retrotransposons

Nature, Nov. 14, 2012; epub ahead of print
Grewal et al.


The DNA Virus Invertebrate Iridescent Virus 6 is a Target of the Drosophila RNAi Machinery

Proceedings of the National Academy of Sciences, Nov. 14, 2012; epub ahead of print
van Rij et al.


A Mesoporous Silica Nanoparticle-PEI-Fusogenic Peptide System for siRNA Delivery in Cancer Therapy

Biomaterials, Nov. 17, 2012; epub ahead of print
Gu et al.


HomoTarget: A New Algorithm for Prediction of microRNA Targets in Homo sapiens

Genomics, Nov. 19, 2012; epub ahead of print
Masoudi-Nejad et al.


miR-155 Targets Histone Deacetylase 4 and Impairs Transcriptional Activity of B Cell Lymphoma 6 in the Eμ-miR-155 Transgenic Mouse Model

Proceedings of the National Academy of Sciences, Nov. 19, 2012; epub ahead of print
Croce et al.


Functional In Vivo Delivery of Multiplexed Anti-HIV-1 siRNAs Via a Chemically Synthesized Aptamer with a Sticky Bridge

Molecular Therapy, Nov. 20, 2012; epub ahead of print
Rossi et al.


Argonaute Divides Its RNA Guide into Domains with Distinct Functions and RNA-Binding Properties

Cell, Nov. 21, 2012; epub ahead of print
Zamore et al.


Mediator Regulates Non-Coding RNA Transcription at Fission Yeast Centromeres

Epigenetics & Chromatin, Nov. 21, 2012; epub ahead of print
Thon et al.


Dicer-2 and Piwi-Mediated RNA Interference in Rift Valley Fever Virus-Infected Mosquito Cells

Journal of Virology, Nov. 21, 2012; epub ahead of print
Bouloy et al.


Profiling of T Helper Cell-Derived Small RNAs Reveals Unique Antisense Transcripts and Differential Association of miRNAs with Argonaute Proteins 1 and 2

Nucleic Acids Research, Nov. 26, 2012; epub ahead of print
Polikepahad & Corry


Capturing microRNA Targets Using an RNA-Induced Silencing Complex-Trap Approach

Proceedings of the National Academy of Sciences, Nov. 26, 2012; epub ahead of print
Goodman et al.


GenomeRNAi: A Database for Cell-Based and In Vivo RNAi Phenotypes, 2013 Update

Nucleic Acids Research, Nov. 27, 2012; epub ahead of print
Boutros et al.


RNA Interference Can Be Used to Disrupt Gene Function in Tardigrades

Development Genes and Evolution, Nov. 28, 2012; epub ahead of print
Goldstein et al.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.