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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Dec 6, 2012

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Protection from Feed-Forward Amplification in an Amplified RNAi Mechanism

Cell, Nov. 9, 2012; 151: 4, 885-899
Fire et al.


The Loop Position of shRNAs and Pre-miRNAs is Critical for the Accuracy of Dicer Processing In Vivo

Cell, Nov. 9, 2012; 151: 4, 900-911
Kay et al.


Selective Autophagy Degraded Dicer and Ago2, and Regulates miRNA Activity

Nature Cell Biology, Nov. 11, 2012; epub ahead of print
Vionnet et al.


Dendrimeric Bowties Featuring Hemisphere-Selective Decoration of Ligands for microRNA-Based Therapy

Biomacromolecules, Nov. 12, 2012; epub ahead of print
Luo et al.


Whole-Genome microRNA Screening Identifies Let-7 and miR-18 as Regulators of Germ Layer Formation During Early Embryogenesis

Genes & Development, Nov. 14, 2012; epub ahead of print
Mercola et al.


Conjugating Phosphospermines to siRNAs for Improved Stability in Serum, Intracellular Delivery, and RNAi-Mediated Gene Silencing

Molecular Pharmaceutics, Nov. 14, 2012; epub ahead of print
Lenne-Samuel et al.


RNAi Triggered by Specialized Machinery Silences Developmental Genes and Retrotransposons

Nature, Nov. 14, 2012; epub ahead of print
Grewal et al.


The DNA Virus Invertebrate Iridescent Virus 6 is a Target of the Drosophila RNAi Machinery

Proceedings of the National Academy of Sciences, Nov. 14, 2012; epub ahead of print
van Rij et al.


A Mesoporous Silica Nanoparticle-PEI-Fusogenic Peptide System for siRNA Delivery in Cancer Therapy

Biomaterials, Nov. 17, 2012; epub ahead of print
Gu et al.


HomoTarget: A New Algorithm for Prediction of microRNA Targets in Homo sapiens

Genomics, Nov. 19, 2012; epub ahead of print
Masoudi-Nejad et al.


miR-155 Targets Histone Deacetylase 4 and Impairs Transcriptional Activity of B Cell Lymphoma 6 in the Eμ-miR-155 Transgenic Mouse Model

Proceedings of the National Academy of Sciences, Nov. 19, 2012; epub ahead of print
Croce et al.


Functional In Vivo Delivery of Multiplexed Anti-HIV-1 siRNAs Via a Chemically Synthesized Aptamer with a Sticky Bridge

Molecular Therapy, Nov. 20, 2012; epub ahead of print
Rossi et al.


Argonaute Divides Its RNA Guide into Domains with Distinct Functions and RNA-Binding Properties

Cell, Nov. 21, 2012; epub ahead of print
Zamore et al.


Mediator Regulates Non-Coding RNA Transcription at Fission Yeast Centromeres

Epigenetics & Chromatin, Nov. 21, 2012; epub ahead of print
Thon et al.


Dicer-2 and Piwi-Mediated RNA Interference in Rift Valley Fever Virus-Infected Mosquito Cells

Journal of Virology, Nov. 21, 2012; epub ahead of print
Bouloy et al.


Profiling of T Helper Cell-Derived Small RNAs Reveals Unique Antisense Transcripts and Differential Association of miRNAs with Argonaute Proteins 1 and 2

Nucleic Acids Research, Nov. 26, 2012; epub ahead of print
Polikepahad & Corry


Capturing microRNA Targets Using an RNA-Induced Silencing Complex-Trap Approach

Proceedings of the National Academy of Sciences, Nov. 26, 2012; epub ahead of print
Goodman et al.


GenomeRNAi: A Database for Cell-Based and In Vivo RNAi Phenotypes, 2013 Update

Nucleic Acids Research, Nov. 27, 2012; epub ahead of print
Boutros et al.


RNA Interference Can Be Used to Disrupt Gene Function in Tardigrades

Development Genes and Evolution, Nov. 28, 2012; epub ahead of print
Goldstein et al.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.