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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Oct 11, 2012

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A Novel In Vivo siRNA Delivery System Specifically Targeting Liver Cells for Protection of ConA-Induced Fulminant Hepatitis

PLoS One, Sept. 6, 2012; epub ahead of print

Min et al.


siRNAs Conjugated with Aromatic Compounds Induce RISC-Mediated Antisense Strand Selection and Strong Gene-Silencing Activity

Biochemical and Biophysical Research Communications, Sept. 7, 2012; epub ahead of print
Seyama et al.


Small RNA Deep Sequencing Reveals a Distinct miRNA Signature Released in Exosomes from Prion-Infected Neuronal Cells

Nucleic Acids Research, Sept. 10, 2012; epub ahead of print
Hill et al.


SID-5 is an Endosome-Associated Protein Required for Efficient Systemic RNAi in C. Elegans

Current Biology, Sept. 11, 2012; epub ahead of print
Hunter et al.


Context-Specific microRNA Analysis: Identification of Functional microRNAs and Their mRNA Targets

Nucleic Acids Research, Sept. 12, 2012; epub ahead of print
Domany et al.


“Seed-Milarity” Confers to hsa-miR-210 and hsa-miR-247b Similar Functional Activity

PLoS One, Sept 13, 2012; epub ahead of print
Mari et al.


Enhancement of Gene Silencing Effect and Membrane Permeability by Peptide-Conjugated 27-Nucleotide Small Interfering RNA

Molecules, Sept. 14, 2012; 17: 9, 11089-11102
Seyama et al.


A Comprehensive Analysis of Precursor microRNA Cleavage by Human Dicer

RNA, Sept. 14, 2012; epub ahead of print
Zeng et al.


RNA Interference Regulates the Cell Cycle Checkpoint through the RNA Export Factor, Ptr1, in Fission Yeast

Biochemical and Biophysical Research Communications, Sept. 16, 2012; epub ahead of print
Kobayashi et al.


Detrimental Effects of RNAi: A Cautionary Note on Its Use in Drosophila Ageing Studies

PLoS One, Sept 17, 2012; epub ahead of print
Partridge et al.


Rapid Intraspecific Evolution of miRNA and siRNA Genes in the Mosquito Aedes aegypti

PLoS one, Sept. 21, 2012; epub ahead of print
Black et al.


microRNA-29a Suppresses Cell Proliferation by Targeting SPARC in Hepatocellular Carcinoma

International Journal of Molecular Medicine, Sept. 25, 2012; epub ahead of print
Wu et al.


Regression of Atherosclerosis in Apolipoprotein E-Deficient Mice by Lentivirus-Mediated Gene Silencing of Lipoprotein-Associated Phospholipase A(2)

Biochemical and Biophysical Research Communications, Sept. 26, 2012; epub ahead of print
Li et al.


A Global Down-Regulation of microRNAs Occurs in Human Quiescent Satellite Cells During Myogenesis

Differentiation, Sept. 26, 2012; epub ahead of print
Harmsen et al.


Convergent Transmission of RNAi Guide-Target Mismatch Information across Argonaute Internal Allosteric Network

PLoS Computational Biology, Sept. 27, 2012; epub ahead of print
Joseph & Osman


Does Base-Pairing Strength Play a Role in microRNA Repression?

RNA, Sept. 27, 2012; epub ahead of print
Heifetz et al.


microRNAs from the Same Precursor Have Different Targeting Properties

Silence, Sept. 27, 2012; epub ahead of print
Griffiths-Jones et al.


microRNA Expression Profiles of Whole Blood in Lung Adenocarcinoma

PLoS One, Sept. 28, 2012; epub ahead of print
Vachani et al.


Hairpin Priming is Better-Suited than In Vitro Polyadenylation to Generate cDNA for Plant miRNA qPCR

Molecular Plant, Sept. 30, 2012; epub ahead of print
Subramanian et al.

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.