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In Print: Last Month's RNAi- and microRNA-Related Papers of Note: Nov 10, 2011


RNAi- and microRNA-Related Papers Published October 2011

Impact of Delivery Systems on siRNA Immune Activation and RNA Interference

Immunology Letters, Oct. 6, 2011; epub ahead of print
Vollmer et al.

Two Classes of Silencing RNAs Move Between Caenorhabditis elegans Tissues

Nature Structural & Molecular Biology, Oct. 9, 2011; epub ahead of print
Hunter et al.

Short Interfering RNAs Induce Retinal Degeneration Via TLR4 and IRF3

Molecular Therapy, Oct. 11, 2011; epub ahead of print
Ambati et al.

Delivery of siRNA to the Mouse Lung Via a Functionalized Lipopolyamine

Molecular Therapy, Oct. 11, 2011; epub ahead of print
Geick et al.

HIVsirDB: a Database of HIV-Inhibiting siRNAs

PLoS One, Oct. 11, 2011; epub ahead of print
Kumar et al.

RNAi Promotes Heterochromatic Silencing Through Replication-Coupled Release of RNA Pol II

Nature, Oct. 16, 2011; epub ahead of print
Martienssen et al.

A Fitness Assay for Comparing RNAi Effects Across Multiple C. elegans Genotypes

BMC Genomics, Oct. 17, 2011; 12: 510
Poulin et al.

A Systematic Screen for microRNAs Regulating the Canonical Wnt Pathway

PLoS One, Oct. 17, 2011; epub ahead of print
Dasgupta et al.

Inhibition of miR-33a/b in Non-Human Primates Raises Plasma HDL and Lowers VLDL Triglycerides

Nature, Oct. 19, 2011; 478: 7369, 404-407
Moore et al.

microRNAs Play Critical Roles in the Survival and Recovery of Caenorhabditis elegans from Starvation-Induced L1 Diapause

Proceedings of the National Academy of Sciences, Oct. 19, 2011; epub ahead of print
Han et al.

Feed-Forward Microprocessing and Splicing at a microRNA-Containing Intron

PLoS Genetics, Oct. 20, 2011; epub ahead of print
Novina et al.

Polymerase II Promoter Strength Determines Efficacy of microRNA-Adapted shRNAs

PLoS One, Oct. 21, 2011; epub ahead of print
McManus et al.

miR-34 miRNAs Provide a Barrier for Somatic Cell Reprogramming

Nature Cell Biology, Oct. 23, 2011; 13: 11, 1353-1360
He et al.

Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease

Molecular Therapy, Oct. 25, 2011; epub ahead of print
Davidson et al.

Strand Antagonism in RNAi: an Explanation of Differences in Potency Between Intracellularly Expressed siRNA and shRNA

Nucleic Acids Research, Oct. 28, 2011; epub ahead of print
Zhou et al.

Long-Term RNA Interference Gene Therapy in a Dominant Retinitis Pigmentosa Mouse Model

Proceedings of the National Academy of Sciences, Oct. 31, 2011; epub ahead of print
Baehr et al.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.