By Doug Macron

Pfizer has stepped back from its goal of filing an investigational new drug application on an internally developed RNAi drug by the end of next year as it evaluates alternative technologies, Gene Silencing News has learned.

The big pharma's Research Technology Center still anticipates filing an IND before the end of 2011, but now expects it to be for "an in-house nucleic acid drug" in 2011, rather than one necessarily based on RNAi.

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A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.