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Peter Buckel, Sigma-Aldrich, Dharmacon

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People in the News

Peter Buckel has stepped down as CEO of Atugen following the company's recent acquisition by UK-based SR Pharma.

Buckel joined Atugen early last year (see RNAi News, 4/23/2004) after serving as CEO of Xantos Biomedicine, a company he co-founded. Prior to this, he was senior vice president of molecular medicine for Roche Diagnostics.

Products & Services

Sigma-Aldrich said this week that it is offering its Mission TRC shRNA library as purified plasmid DNA. This is in addition to the frozen bacterial glycerol stock format the company currently offers.

Sigma-Aldrich said it is offering the library in the new format through an exclusive arrangement with The Broad Institute's RNAi Consortium.

The consortium — which was designed to create a library of RNAi molecules against virtually all human and mouse genes — includes six research institutions: Massachusetts General Hospital, Harvard Medical School, Dana-Farber Cancer Institute, The Broad Institute, Whitehead Institute for Biomedical Research, and the Massachusetts Institute of Technology.

Other members include five life science organizations: Bristol-Myers Squibb, Eli Lilly, Novartis, Sigma-Aldrich, and the Taiwan government-sponsored academic Academia Sinica-National Science Council. Each of these member organizations will contribute $3.6 million over three years to support the consortium, the Broad Institute stated.


Dharmacon said this week that it has released a human genome-wide siRNA library.

According to Dharmacon, the library includes more than 100,000 siRNA reagents targeting over 21,000 human genes contained in the NCBI RefSeq database. A Smartpool siRNA reagent and four individual siRNAs are available for each human gene, the company noted.

The Scan

Driving Malaria-Carrying Mosquitoes Down

Researchers from the UK and Italy have tested a gene drive for mosquitoes to limit the spread of malaria, NPR reports.

Office Space to Lab Space

The New York Times writes that some empty office spaces are transforming into lab spaces.

Prion Pause to Investigate

Science reports that a moratorium on prion research has been imposed at French public research institutions.

Genome Research Papers on Gut Microbe Antibiotic Response, Single-Cell RNA-Seq Clues to Metabolism, More

In Genome Research this week: gut microbial response to antibiotic treatment, approach to gauge metabolic features from single-cell RNA sequencing, and more.