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People in the News: David Lewis; David Rozema


Arrowhead Research announced that it has named David Lewis as its vice president of biology, and David Rozema as its vice president of chemistry.

Lewis and Rozema recently joined Arrowhead through the company's recent acquisition of Roche's Madison, Wis.-based RNA therapeutic operations (GSN 10/27/2011).

Lewis will oversee operations at the Madison facility and handle preclinical research and developments there. Rozema will supervise the development and synthesis of siRNA delivery vehicles.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.