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People in the News: Aug 18, 2011

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Addex Pharmaceuticals, a developer of allosteric modulators, has named Bharat Chowrira as its CEO.

Chowrira previously served as senior vice president and COO of Nektar Therapeutics. Before that, he was executive director of worldwide licensing and external research at Merck. He joined Merck after the company acquired Sirna Therapeutics, where Chowrira was vice president of legal affairs and patent counsel.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.