By Molika Ashford

MiR-548d may play a super-regulatory role in pancreatic cancer, affecting multiple components of the signaling pathways associated with the disease, a recent study by Hannover Medical School researchers has reported.

Using a bioinformatics-based approach, the group analyzed potential miRNA-binding sites in pancreatic cancer-associated pathways, calculating the key miRNAs in these regulatory networks and narrowing the set down to those with the most central role.