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Papers of Note Published September 2011


RNAi- and microRNA-Related Papers Published September 2011

Optimized Tandem amiRNA Mediates Stronger Inhibitory Effects on Hepatitis B Virus Infection

Journal of Gastrointestinal and Liver Diseases, Sept. 2011; 20: 3, 271-278
Gao et al.

Germline Deletion of the miR-17~92 Cluster Causes Skeletal and Growth Defects in Humans

Nature Genetics, Sept. 4, 2011; epub ahead of print
Amiel et al.

Defects in RNA Quality Control Factors Reveal RNAi-Independent Nucleation of Heterochromatin

Nature Structural & Molecular Biology, Sept. 4, 2011; epub ahead of print
Grewal et al.

Competition Between ADAR and RNAi Pathways for an Extensive Class of RNA Targets

Nature Structural & Molecular Biology, Sept. 11, 2011; epub ahead of print
Fire et al.

Deep Sequencing of Virus-Infected Cells Reveals HIV-Encoded Small RNAs

Nucleic Acids Research, Sept. 12, 2011; epub ahead of print
Berkhout et al.

Dicer is Required for Haploid Male Germ Cell Differentiation in Mice

PLoS One, Sept. 16, 2011; epub ahead of print
Kotaja et al.

Compatibility with Killer Explains the Rise of RNAi-Deficient Fungi

Science, Sept. 16, 2011; 333: 6049, 1592
Bartel et al.

microRNA-Binding is Required for Recruitment of Human Argonaute 2 to Stress Granules and P-Bodies

Biochemical and Biophysical Research Communications; Sept. 17, 2011; epub ahead of print
Hobman et al.

A Study of the Evolution of Human microRNAs by Their Apparent Repression Effectiveness on Target Genes

PLoS One, Sept. 21, 2011; epub ahead of print
Huang & Gu

Expanding the Action of Duplex RNAs into the Nucleus: Redirecting Alternative Splicing

Nucleic Acids Research, Sept. 23, 2011; epub ahead of print
Corey et al.

Rational Design of Therapeutic siRNAs: Minimizing Off-Targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease

Molecular Therapy, Sept. 27, 2011; epub ahead of print
Davidson et al.

RNA-Based Immunity Terminates Viral Infection in Adult Drosophila in Absence of Viral Suppression of RNAi: Characterization of Viral siRNA Populations in Wildtype and Mutant Flies

Journal of Virology, Sept. 28, 2011; epub ahead of print
Ding et al.

miRNA-Dependent Gene Silencing Involving Ago2-Mediated Cleavage of a Circular Antisense RNA

EMBO Journal, Sept. 30, 2011; epub ahead of print
Kjems et al.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.