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Papers of Note: Jul 9, 2009

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RNAi-Related Papers Published June 2009

Specific Knockdown of GAD67 in the Striatum Using Naked Small Interfering RNAs

Journal of Biotechnology, June 2, 2009; epub ahead of print
Duflo et al.


Chitosan-Graft-Polyethylenimine for Akt1 siRNA Delivery to Lung Cancer Cells

International Journal of Pharmaceutics
, June 6, 2009; epub ahead of print
Cho et al.


RNAi-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy

Antimicrobial Agents and Chemotherapy
, June 8, 2009; epub ahead of print
Meyers et al.


Secondary RNA Structure and Its Role in RNA Interference to Silence the Respiratory Syncytial Virus Fusion Protein Gene

Molecular Biotechnology
, June 9, 2009; epub ahead of print
Singh et al.


Imaging Individual microRNAs in Single Mammalian Cells In Situ

Nucleic Acids Research
, June 10, 2009; epub ahead of print
Lu & Tsourkas


Viral Suppressors of RNA Silencing Hinder Exogenous and Endogenous Small RNA Pathways in Drosophila

PLoS One, June 10, 2009; 4: 6, e5866
Antoniewski et al.


Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

Cell, June 12, 2009; 137: 6, 1005-1017
Mendell et al.


Dual-Target Gene Silencing by Using Long, Synthetic siRNA Duplexes Without Triggering Antiviral Responses

Molecules and Cell, June 12, 2009; epub ahead of print
Lee et al.


A Novel and Universal Method for microRNA RT-qPCR Data Normalization

Genome Biology, June 16, 2009; epub ahead of print
Vandesompele et al.


Allele-Specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease

Molecular Therapy, June 16, 2009; epub ahead of print
Paulson et al.


A Recombinase-Based Palindrome Generator Capable of Producing Randomized shRNA Libraries

Journal of Biotechnology, June 17, 2009; epub ahead of print
Nichols & Steinman


Argonaute HITS-CLIP Decodes microRNA-mRNA Interaction Maps

Nature, June 17, 2009; epub ahead of print
Darnell et al.


Efficient Oligonucleotide-Mediated Degradation of Nuclear Non-Coding RNAs in Mammalian Cultured Cells

RNA, June 17, 2009; epub ahead of print
Hirose et al.


microRNA-Mediated Gene Silencing Modulates the UV-Induced DNA-Damage Response

EMBO Journal, June 18, 2009; epub ahead of print
Persengiev et al.


Abundant Primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila Ovary Cell Line

Genome Research, June 18, 2009; epub ahead of print
Lai et al.


Reconstructing Signaling Pathways from RNAi Data Using Probabilistic Boolean Threshold Networks

Bioinformatics, June 19, 2009; epub ahead of print
Bartenschlager et al.


Endogenous tasiRNAs Mediate Non-Cell Autonomous Effects on Gene Regulation in Arabidopsis thaliana

PLoS One, June 19, 2009; 4: 6, e5980
Martienssen et al.


In Vivo Manipulation of Gene Expression in Non-Human Primates Using Lentiviral Vectors as Delivery Vehicles

Methods, June 23, 2009; epub ahead of print
Ojeda et al.


Discovering Ligands for a microRNA Precursor with Peptoid Microarrays

Nucleic Acids Research, June 26, 2009; epub ahead of print
Luebke et al.


Synthetic Heterochromatin Bypasses RNAi and Centromeric Repeats to Establish Functional Centromeres

Science, June 26, 2009; 324: 5935, 1716-1719
Allshire et al.


microRNA-Mediated Switching of Chromatin-Remodeling Complexes in Neural Development

Nature, June 28, 2009; epub ahead of print
Crabtree et al.


High-Resolution Profiling and Discovery of Planarian Small RNAs

Proceedings of the National Academy of Sciences, June 29, 2009; epub ahead of print
Rajewsky et al.

The Scan

Highly Similar

Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News.

Gain of Oversight

According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research.

Lasker for mRNA Vaccine Work

The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners

PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC

In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.