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Papers of Note for April 2009


Simple Construction of Plant RNAi Vectors Using Long Oligonucleotides

Journal of Plant Research, April 4, 2009; epub ahead of print
Matsui et al.

Five siRNAs Targeting Three SNPs May Provide Therapy for Three-Quarters of Huntington's Disease Patients

Current Biology, April 8, 2009; epub ahead of print
Aronin et al.

Cell-Cell Contact Globally Activates microRNA Biogenesis

Proceedings of the National Academy of Sciences, April 9, 2009; epub ahead of print
Mendell et al.

Genome-Wide Analysis of Notch Signaling in Drosophila by Transgenic RNAi

Nature, April 12, 2009; epub ahead of print
Knoblich et al.

Embryonic Stem Cell-Specific microRNAs Promote Induced Pluripotency

Nature Biotechnology, April 12, 2009; epub ahead of print
Blelloch et al.

Differential RNA Silencing-Suppression Activity of NS1 Proteins from Different Influenza A Strains

Journal of General Virology, April 15, 2009; epub ahead of print
Berkhout et al.

Spatial Regulation of Specific Gene Expression Through Photoactivation of RNAi

Journal of Controlled Release, April 16, 2009; epub ahead of print
Ohtsuki et al.

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A Robust Methodology to Study Urine microRNA as Tumor Marker: microRNA-126 and microRNA-182 are Related to Urinary Bladder Cancer

Urologic Oncology, April 16, 2009; epub ahead of print
Sczakiel et al.

A microRNA Imparts Robustness Against Environmental Fluctuation During Development

Cell, April 17, 2009; 137(2): 273-282
Carthew et al.

Molecular Genetics and Comparative Genomics Reveal RNAi is Not Functional in Malaria Parasites

Nucleic Acids Research, April 20, 2009; epub ahead of print
de Koning-Ward et al.

A Novel Short Hairpin RNA-Expression System Promotes Sox9-Dependent Gene Silencing

Plasmid, April 20, 2009; epub ahead of print
Hickok et al.

Stringent Testing Identified Highly Potent and Escape-Proof Anti-HIV Short Hairpin RNAs

Journal of Gene Medicine
, April 21, 2009; epub ahead of print
Berkhout et al.

Allelic Imbalance Sequencing Reveals that Single-Nucleotide Polymorphisms Frequently Alter microRNA-Directed Repression

Nature Biotechnology, April 26, 2009; epub ahead of print
Kim & Bartel

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Mammalian GW182 Contains Multiple Argonaute-Binding Sites and Functions in microRNA-Mediated Translational Repression

RNA, April 27, 2009; epub ahead of print
Yokoyama et al.

The Effects of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice

Molecular Therapy, April 28, 2009; epub ahead of print
Kjems et al.

Novel microRNAs Encoded by Herpesvirus of Turkeys: Evidence of miRNA Evolution by Duplication

Journal of Virology, April 29, 2009; epub ahead of print
Nair et al.

Caged siRNAs for Spatiotemporal Control of Gene Silencing

Molecular Pharmaceutics, April 29, 2009; epub ahead of print
Monroe et al.

Both Strands of siRNA Have Potential to Guide Post-Transcriptional Gene Silencing in Mammalian Cells

PLoS One, April 29, 2009; epub ahead of print
Yang et al.

Combined Antiviral Activity of Interferon-Alpha and RNA Interference Directed Against Hepatitis C Without Affecting Vector Delivery and Gene Silencing

Journal of Molecular Medicine
, April 30, 2009; epub ahead of print
van der Laan et al.

DIANA-microT Web Server: Elucidating microRNA Functions Through Target Prediction

Nucleic Acids Research, April 30, 2009; epub ahead of print
Hatzigeorgiou et al.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Gene Linked to Alkaline Sensitivity in Plants Identified

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.