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Papers of Note for April 2009

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Simple Construction of Plant RNAi Vectors Using Long Oligonucleotides

Journal of Plant Research, April 4, 2009; epub ahead of print
Matsui et al.


Five siRNAs Targeting Three SNPs May Provide Therapy for Three-Quarters of Huntington's Disease Patients

Current Biology, April 8, 2009; epub ahead of print
Aronin et al.


Cell-Cell Contact Globally Activates microRNA Biogenesis

Proceedings of the National Academy of Sciences, April 9, 2009; epub ahead of print
Mendell et al.


Genome-Wide Analysis of Notch Signaling in Drosophila by Transgenic RNAi

Nature, April 12, 2009; epub ahead of print
Knoblich et al.


Embryonic Stem Cell-Specific microRNAs Promote Induced Pluripotency

Nature Biotechnology, April 12, 2009; epub ahead of print
Blelloch et al.


Differential RNA Silencing-Suppression Activity of NS1 Proteins from Different Influenza A Strains

Journal of General Virology, April 15, 2009; epub ahead of print
Berkhout et al.


Spatial Regulation of Specific Gene Expression Through Photoactivation of RNAi

Journal of Controlled Release, April 16, 2009; epub ahead of print
Ohtsuki et al.

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A Robust Methodology to Study Urine microRNA as Tumor Marker: microRNA-126 and microRNA-182 are Related to Urinary Bladder Cancer

Urologic Oncology, April 16, 2009; epub ahead of print
Sczakiel et al.


A microRNA Imparts Robustness Against Environmental Fluctuation During Development

Cell, April 17, 2009; 137(2): 273-282
Carthew et al.


Molecular Genetics and Comparative Genomics Reveal RNAi is Not Functional in Malaria Parasites

Nucleic Acids Research, April 20, 2009; epub ahead of print
de Koning-Ward et al.


A Novel Short Hairpin RNA-Expression System Promotes Sox9-Dependent Gene Silencing

Plasmid, April 20, 2009; epub ahead of print
Hickok et al.


Stringent Testing Identified Highly Potent and Escape-Proof Anti-HIV Short Hairpin RNAs

Journal of Gene Medicine
, April 21, 2009; epub ahead of print
Berkhout et al.


Allelic Imbalance Sequencing Reveals that Single-Nucleotide Polymorphisms Frequently Alter microRNA-Directed Repression

Nature Biotechnology, April 26, 2009; epub ahead of print
Kim & Bartel

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Mammalian GW182 Contains Multiple Argonaute-Binding Sites and Functions in microRNA-Mediated Translational Repression

RNA, April 27, 2009; epub ahead of print
Yokoyama et al.


The Effects of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice

Molecular Therapy, April 28, 2009; epub ahead of print
Kjems et al.


Novel microRNAs Encoded by Herpesvirus of Turkeys: Evidence of miRNA Evolution by Duplication

Journal of Virology, April 29, 2009; epub ahead of print
Nair et al.


Caged siRNAs for Spatiotemporal Control of Gene Silencing

Molecular Pharmaceutics, April 29, 2009; epub ahead of print
Monroe et al.


Both Strands of siRNA Have Potential to Guide Post-Transcriptional Gene Silencing in Mammalian Cells

PLoS One, April 29, 2009; epub ahead of print
Yang et al.


Combined Antiviral Activity of Interferon-Alpha and RNA Interference Directed Against Hepatitis C Without Affecting Vector Delivery and Gene Silencing

Journal of Molecular Medicine
, April 30, 2009; epub ahead of print
van der Laan et al.


DIANA-microT Web Server: Elucidating microRNA Functions Through Target Prediction

Nucleic Acids Research, April 30, 2009; epub ahead of print
Hatzigeorgiou et al.

The Scan

Omicron's Emergence

The World Health Organization has called Omicron a SARS-CoV-2 "variant of concern," the Los Angeles Times writes.

Not as Much

Merck's pill to treat COVID-19 reduces the risk of hospitalization and death among COVID-19 patients by less than previously reported, the New York Times says.

Bats That Hang Together

Discover magazine writes that researchers have found a social microbiome among vampire bats.

PLOS Papers on CEWAS, Simian Varicella Virus Transcriptome, Dermatomyositis Markers

In PLOS this week: multi-omic approach to home in on genetic risk variants, transcriptomic analysis of the simian varicella virus, and more.