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Papers of Note: Sep 2, 2010

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RNAi- and microRNA-Related Papers Published August 2010

In Vivo RNAi-Mediated Silencing of TAK1 Decreases Inflammatory Th1 and Th17 Cells through Targeting of Myeloid Cells

Blood, Aug. 3, 2010; epub ahead of print
Gross et al.


Argonaute Proteins are Key Determinants of RNAi Efficacy, Toxicity, and Persistence in the Adult Mouse Liver

Journal of Clinical Investigation, Aug. 9, 2010; epub ahead of print
Kay et al.


Conserved Vertebrate miR-451 Provides a Platform for Dicer-Independent, Ago2-Mediated microRNA Biogenesis

Proceedings of the National Academy of Sciences, Aug. 10, 2010; epub ahead of print
Lai et al.


Inhibition of Adenovirus Infections by siRNA-Mediated Silencing of Early and Late Adenoviral Gene Functions

Antiviral Research, Aug. 11, 2010; epub ahead of print
Fechner et al.


Functional microRNA Generated from a Cytoplasmic RNA Virus

Nucleic Acids Research, Aug. 12, 2010; epub ahead of print
Mandl et al.


Smad Proteins Bind a Conserved RNA Sequence to Promote microRNA Maturation by Drosha

Molecular Cell, Aug. 13, 2010; 39: 3, 373-384
Hata et al.


MeCP2 Controls BDNF Expression and Cocaine Intake through Homeostatic Interactions with microRNA-212

Nature Neuroscience, Aug. 15, 2010; epub ahead of print
Kenny et al.


Canonical and Alternate Functions of the microRNA Biogenesis Machinery

Genes & Development, Aug. 16, 2010; epub ahead of print
Littman et al.


Position-Dependent Effects on Stability in Tricyclo-DNA-Modified Oligonucleotide Duplexes

Nucleic Acids Research, Aug. 17, 2010; epub ahead of print
Leumann et al.


Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery

Bioconjugate Chemistry, Aug. 18, 2010; 21: 8, 1448-1454
Anderson et al.


A Comprehensive Survey of 3' Animal miRNA-Modification Events and a Possible Role for 3' Adenylation in Modulating miRNA Targeting Effectiveness

Genome Research, Aug. 18, 2010; epub ahead of print
Daub et al.


Design and Assembly of New Non-Viral RNAi Delivery Agents by Microwave-Assisted Quaternization of Tertiary Amines

Bioconjugate Chemistry, Aug. 19, 2010; epub ahead of print
Rana et al.


Muscle-Specific microRNAs are Regulated by Endurance Exercise in Human Skeletal Muscle

Journal of Physiology, Aug. 19, 2010; epub ahead of print
Laye et al.


Suppression of Hepatitis B Virus Replication by microRNA-199a-3p and microRNA-210

Antiviral Research, Aug. 20, 2010; epub ahead of print
Tang et al.


Deep Sequencing of the Small RNA Transcriptome of Normal and Malignant Human B Cells Identifies Hundreds of Novel microRNAs

Blood, Aug. 23, 2010; epub ahead of print
Dave et al.


Hairpin dsRNA Does Not Trigger RNA Interference in Candida albicans Cells

Yeast, Aug. 24, 2010; epub ahead of print
Marr et al.


Structural Basis of microRNA Length Variety

Nucleic Acids Research, Aug. 25, 2010; epub ahead of print
Krzyzosiak et al.


ncRNAimprint: A Comprehensive Database of Mammalian Imprinted Non-Coding RNAs

RNA, Aug. 26, 2010; epub ahead of print
Qu et al.


miRNAkey: A Software for microRNA Deep Sequencing Analysis

Bioinformatics, Aug. 27, 2010; epub ahead of print
Shomron et al.


Highly Efficient siRNA-Delivery System into Human and Murine Cells Using Single-Well Carbon Nanotubes

Nanotechnology, Aug. 27, 2010; epub ahead of print
Guatimosim et al.

The Scan

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.

Estonian Biobank Team Digs into Results Return Strategies, Experiences

Researchers in the European Journal of Human Genetics outline a procedure developed for individual return of results for the population biobank, along with participant experiences conveyed in survey data.

Rare Recessive Disease Insights Found in Individual Genomes

Researchers predict in Genome Medicine cross-population deletions and autosomal recessive disease impacts by analyzing recurrent nonallelic homologous recombination-related deletions.

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.