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Papers of Note: Aug 12, 2010

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RNAi- and microRNA-Related Papers Published July 2010

RNAi-Based Treatment for Neovascular Age-Related Macular Degeneration by Sirna-027

American Journal of Ophthalmology, July 2010; 150: 1, 33-39
Nguyen et al.


tRNA(Lys3) Promoter Cassettes that Efficiently Express RNAi-Activating Anti-Hepatitis B Virus Short Hairpin RNAs

Biochemical and Biophysical Research Communications, July 1, 2010; epub ahead of print
Arbuthnot et al.


Enhanced Target Gene Knockdown by a Bifunctional shRNA: a Novel Approach of RNA Interference

Cancer Gene Therapy, July 2, 2010; epub ahead of print
Nemunaitis et al.


Adverse Interactions Between microRNAs and Target Genes from Different Species

Proceedings of the National Academy of Sciences, July 6, 2010; epub ahead of print
Wu et al.


Export of microRNAs and microRNA-Protective Protein by Mammalian Cells

Nucleic Acids Research, July 7, 2010; epub ahead of print
Galas et al.


Carbonate Apatite-Facilitated Intracellularly Delivered siRNA for Efficient Knockdown of Functional Genes

Journal of Controlled Release, July 8, 2010; epub ahead of print
Akaike et al.


Non-Invasive Imaging of Lipid Nanoparticle-Mediated Systemic Delivery of Small Interfering RNA to the Liver

Molecular Therapy, July 13, 2010; epub ahead of print
Sepp-Lorenzino et al.


Pro-Inflammatory Role for let-7 microRNA in Experimental Asthma

Journal of Biological Chemistry, July 14, 2010; epub ahead of print
Corry et al.


Quantitative Analysis of Conditional Gene Inactivation Using Rationally Designed, Tetracycline-Controlled miRNAs

Nucleic Acids Research, July 17, 2010; epub ahead of print
Bartsch et al.


A Direct Role for Hsp90 in Pre-RISC Formation in Drosophila

Nature Structural & Molecular Biology, July 18, 2010; epub ahead of print
Siomi et al.


Combined Agonist-Antagonist Genome-Wide Functional Screening Identifies Broadly Active Antiviral microRNAs

Proceedings of the National Academy of Sciences, July 19, 2010; epub ahead of print
Buck et al.


22-Nucleotide RNAs Trigger Secondary siRNA Biogenesis in Plants

Proceedings of the National Academy of Sciences, July 19, 2010; epub ahead of print
Wu et al.


A KRAS Variant in Ovarian Cancer Acts as a Genetic Marker of Cancer Risk

Cancer Research, July 20, 2010; epub ahead of print
Weidhaas et al.


Enhanced Induction of HIV-Specific Cytotoxic T Lymphocytes by Dendritic Cell-Targeted Delivery of SOCS-1 siRNA

Molecular Therapy, July 20, 2010; epub ahead of print
Shankar et al.


Identification of Novel microRNA-Like Molecules Generated from Herpesvirus and Host tRNA Transcripts

Journal of Virology, July 21, 2010; epub ahead of print
Virgin et al.


The Terminal Loop Region Controls microRNA Processing by Drosha and Dicer

Nucleic Acids Research, July 21, 2010; epub ahead of print
Zhang & Zeng


In Vivo Application of an RNAi Strategy for the Selective Suppression of a Mutant Allele

Human Gene Therapy, July 22, 2010; epub ahead of print
Yokota et al.


Identification of a microRNA Signature of Renal Ischemia Reperfusion Injury

Proceedings of the National Academy of Sciences, July 22, 2010; epub ahead of print
Iacomini et al.


microRNA Expression Variability in Human Cervical Tissues

PLoS One, July 26, 2010; 5: 7, e11780
Santos et al.


microRNAs Enriched in Hematopoietic Stem Cells Differentially Regulate Long-Term Hematopoietic Output

Proceedings of the National Academy of Sciences, July 26, 2010; epub ahead of print
Baltimore et al.


Chlorotoxin-Bound Magnetic Nanovector Tailored for Cancer Cell Targeting, Imaging, and siRNA Delivery

Biomaterials, July 28, 2010; epub ahead of print
Zhang et al.


Developmental RNA Processing of 3' UTRs in Hox mRNA as a Context-Dependent Mechanism Modulating Visibility to microRNAs

Development, July 28, 2010; epub ahead of print
Alonso et al.


Pathogenic LRRK2 Negatively Regulates microRNA-Mediated Translational Repression

Nature, July 29, 2010; 466: 7306, 637-641
Lu et al.


The miR-15/107 Group of microRNA Genes: Evolutionary Biology, Cellular Functions, and Roles in Human Diseases

Journal of Molecular Biology, July 30, 2010; epub ahead of print
Nelson et al.

The Scan

Dropped Charges

The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal.

More Kids

The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children.

PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS

In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more.

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.