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Papers of Note: Jul 8, 2010

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RNAi- and microRNA-Related Papers Published June 2010

Vectors and Parameters That Enhance the Efficacy of RNAi-Mediated Gene Disruptions in Transgenic Drosophila

Proceedings of the National Academy of Sciences, June 4, 2010; epub ahead of print
Levine et al.


Identification of Small Molecules That Suppress microRNA Function and Reverse Tumorigenesis

Journal of Biological Chemistry
, June 7, 2010; epub ahead of print
Jeang et al.


Deriving Four Functional anti-HIV siRNAs from a Single Pol III-Generated Transcript Comprising Two Adjacent Long Hairpin RNA Precursors

Nucleic Acids Research, June 4, 2010; epub ahead of print
Weinberg et al.


Tracking Differentiating Neural Progenitors in Pluripotent Cultures Using microRNA-Regulated Lentiviral Vectors

Proceedings of the National Academy of Sciences, June 7, 2010; epub ahead of print
Jakobsson et al.


Engineered RNA Viral Synthesis of microRNAs

Proceedings of the National Academy of Sciences, June 7, 2010; epub ahead of print
Tenoever et al.


Anticipating and Blocking HIV-1 Escape by Second-Generation Antiviral shRNAs

Retrovirology, June 8, 2010; epub ahead of print
Berkhout et al.


Circulating microRNAs are New and Sensitive Biomarkers of Myocardial Infarction

European Heart Journal, June 9, 2010; epub ahead of print
Capogrossi et al.


Naturally Occurring Variations in Sequence Length Creates microRNA Isoforms that Differ in Argonaute Effector Complex Specificity

Silence, June 9, 2010; epub ahead of print
Fahlman et al.


Small Regulatory RNAs Inhibit RNA Polymerase II During the Elongation Phase of Transcription

Nature, June 13, 2010; epub ahead of print
Kennedy et al.


Identification of Sequence Features That Predict Competition Potency of siRNAs

Biochemical and Biophysical Research Communications, June 15, 2010; epub ahead of print
Lee et al.


miR-375 Frequently Down-Regulated in Gastric Cancer Inhibits Cell Proliferation by Targeting JAK2

Cell Research, June 15, 2010; epub ahead of print
Zhou et al.


Unique Functionality of 22-nt miRNAs in Triggering RDR6-Dependent siRNA Biogenesis from Target Transcripts in Arabidopsis

Nature Structural & Molecular Biology, June 18, 2010; epub ahead of print
Carrington et al.


Down-Regulation of a Host microRNA by a Herpesvirus saimiri Non-Coding RNA

Science, June 18, 2010; 328: 5985, 1563-1566
Steitz et al.


Target RNA-Directed Trimming and Tailing of Small Silencing RNAs

Science, June 18, 2010; 328: 5985, 1534-1539
Zamore et al.


Development of a Lung Cancer Therapeutic Based on Tumor Suppressor microRNA-34

Cancer Research, June 22, 2010; epub ahead of print
Bader et al.


Optimization and Analysis of a Quantitative Real-Time PCR-Based Technique to Determine microRNA Expression in Formalin-Fixed, Paraffin-Embedded Samples

BMC Biotechnology, June 23, 2010; epub ahead of print
Kamel-Reid et al.


In Vitro and In Vivo Targeted Delivery of IL-10 Interfering RNA by JC Virus-Like Particles

Journal of Biomedical Science, June 24, 2010; epub ahead of print
Tsay et al.


Longer 19-Base Pair Short Interfering RNA Duplexes Rather Than Shorter Duplexes Trigger RNA Interference

Oligonucleotides, June 24, 2010; epub ahead of print
Nawrot et al.


Hairpin Transcription Does Not Necessarily Lead to Efficient Triggering of the RNAi Pathway

Transgenic Research, June 26, 2010; epub ahead of print
Kalantidis et al.


microRNA Evolution in a Human Transcription Factor and microRNA Regulatory Network

BMC Systems Biology, June 29, 2010; epub ahead of print
Cui et al.


Modeling of Congenital Erythropoietic Porphyria by RNA Interference: A New Tool for Preclinical Gene Therapy Evaluation

Journal of Gene Medicine, June 29, 2010; epub ahead of print
de Verneuil et al.


microRNA-181a Modulates Gene Expression of Zinc Finger Family Members by Directly Targeting Their Coding Regions

Nucleic Acids Research, June 29, 2010; epub ahead of print
He et al.


MIReNA: Finding microRNAs with High Accuracy and No Learning at Genome Scale and from Deep Sequencing Data

Bioinformatics, June 30, 2010; epub ahead of print
Mathelier & Carbone

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.