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Papers of Note: Feb 4, 2010

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RNAi- and microRNA-Related Papers Published January 2010

Decoding Pooled siRNA Screens by Means of Barcode Tiling Arrays

BMC Genomics, Jan. 5, 2010; epub ahead of print
Hoheisel et al.


Polyethylenimine/Small Interfering RNA-Mediated Knockdown of Vascular Endothelial Growth Factor In Vivo Exerts Anti-Tumor Effects Synergistically with Bevacizumab

Journal of Gene Medicine, Jan. 5, 2010; epub ahead of print
Aigner et al.


Opposing microRNA Families Regulate Self-Renewal in Mouse Embryonic Stem Cells

Nature, Jan. 6, 2010; epub ahead of print
Blelloch et al.


Effective siRNA Inhibit the Replication of Novel Influenza A (H1N1) Virus

Antiviral Research, Jan. 7, 2010; epub ahead of print
Qi et al.


Transcriptional Control of Gene Expression by microRNAs

Cell, Jan. 8, 2010; 140: 1, 111-122
Frank et al.


Hairpin RNA Induces Secondary Small Interfering RNA Synthesis and Silencing in Trans in Fission Yeast

EMBO Reports, Jan. 8, 2010; epub ahead of print
Allshire et al.


Allosteric Regulation of Argonaute Proteins by miRNAs

Nature Structural & Molecular Biology, Jan. 10, 2010; epub ahead of print
Green et al.


Chemosensitization of Cancer Cells by siRNA Using Targeted Nanogel Delivery

BMC Cancer, Jan. 11, 2010; epub ahead of print
McDonald et al.


An Ascovirus-Encoded Ribonuclease III Autoregulates Its Expression and Suppresses RNAi-Mediated Gene Silencing

Journal of Virology, Jan. 13, 2010; epub ahead of print
Asgari et al.


microRNA Expression and Virulence in Pandemic Influenza Virus-Infected Mice

Journal of Virology, Jan. 13, 2010; epub ahead of print
Katze et at.


Functional Genomics Tool: Gene Silencing in Ixodes scapularis Eggs and Nymphs by Electroporated dsRNA

BMC Biotechnology, Jan. 14, 2010; epub ahead of print
Mather et al.


Structure and Activity of Putative Intronic miRNA Promoters

RNA, Jan. 14, 2010; epub ahead of print
Davidson et al.


Genome-Wide RNAi Screen Identifies Human Host Factors Crucial for Influenza Virus Replication

Nature, Jan. 17, 2010; epub ahead of print
Meyer et al.


Mechanisms of Nucleotide Trafficking During siRNA Delivery to Endothelial Cells Using Perfluorocarbon Nanoemulsions

Biomaterials, Jan. 19 2010; epub ahead of print
Wickline et al.


Molecular Mechanisms that Funnel RNA Precursors into Endogenous Small Interfering RNA and microRNA Biogenesis Pathways in Drosophila

RNA, Jan. 19, 2010; epub ahead of print
Siomi et al.


Many Families of C. elegans microRNAs are Not Essential for Development or Viability

Current Biology, Jan. 20, 2010; epub ahead of print
Horvitz et al.


PhenomiR: a Knowledgebase for microRNA Expression in Diseases and Biological Processes

Genome Biology, Jan. 20, 2010; epub ahead of print
Theis et al.


Self-Complementary Sequence Context in Mature miRNAs

Biochemical and Biophysical Research Communications, Jan. 21, 2010; epub ahead of print
Herdewijn et al.


Atypical Transcription of microRNA Gene Fragments

Nucleic Acids Research, Jan. 21, 2010; epub ahead of print
Ramratnam et al.


Additive Effects of Plant-Expressed Double-Stranded RNAs on Root-Knot Nematode Development

International Journal for Parasitology, Jan. 22, 2010; epub ahead of print
McPherson et al.


Tooth Morphogenesis and Ameloblast Differentiation are Regulated by microRNAs

Developmental Biology, Jan. 23, 2010; epub ahead of print
Thesleff et al.


Inhibition of Hepatitis E Virus Replication Using Short Hairpin RNA

Antiviral Research, Jan. 24, 2010; epub ahead of print
Kar et al.


Structural Insights into the Human GW182-PABC Interaction in microRNA-Mediated Deadenylation

Nature Structural & Molecular Biology, Jan. 24, 2010; epub ahead of print
Doudna et al.


Hepatitis C Virus Proteins Modulate microRNA Expression and Chemosensitivity in Malignant Hepatocytes

Clinical Cancer Research, Jan. 26, 2010; epub ahead of print
Patel et al.

The Scan

Y Chromosome Study Reveals Details on Timing of Human Settlement in Americas

A Y chromosome-based analysis suggests South America may have first been settled more than 18,000 years ago, according to a new PLOS One study.

New Insights Into TP53-Driven Cancer

Researchers examine in Nature how TP53 mutations arise and spark tumor development.

Mapping Single-Cell Genomic, Transcriptomic Landscapes of Colorectal Cancer

In Genome Medicine, researchers present a map of single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer.

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.