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Papers of Note: Jan 7, 2010

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RNAi- and microRNA-Related Papers Published December 2009

Minimal-Length Short Hairpin RNAs: the Relationship of Structure and RNAi Activity

RNA, Dec. 1, 2009; epub ahead of print
Johnston et al.


Nanotubes Functionalized with Lipids and Natural Amino Acid Dendrimers: a New Strategy to Create Nanomaterials for Delivering Systemic RNAi

Bioconjugate Chemistry, Dec. 3, 2009; epub ahead of print
Rana et al.


Therapeutic Silencing of microRNA-122 in Primates with Chronic Hepatitis C Virus Infection

Science, Dec. 3, 2009; epub ahead of print
Orum et al.


RNAi-Mediated Viral Immunity Requires Amplification of Virus-Derived siRNAs in Arabidopsis thaliana

Proceedings of the National Academy of Sciences, Dec. 4, 2009; epub ahead of print
Ding et al.


microRNA-Dependent Metamorphosis in Hemimetabolan Insects

Proceedings of the National Academy of Sciences, Dec. 4, 2009; epub ahead of print
Gomez-Orte & Belles


ATP-Dependent Human RISC Assembly Pathways

Nature Structural & Molecular Biology, Dec. 6, 2009; epub ahead of print
Tomari et al.


Regression of Murine Lung Tumors by the let-7 microRNA

Oncogene, Dec. 7, 2009; epub ahead of print
Slack et al.


microRNAs Align with Accessible Sites in Target mRNAs

Journal of Cellular Biochemistry, Dec. 8, 2009; epub ahead of print
Clawson et al.


Pseudovirions as Vehicles for the Delivery of siRNA

Pharmaceutical Research, Dec. 9, 2009; epub ahead of print
Kimchi-Sarfaty et al.


AAV-Mediated Knockdown of Peripherin-2 In Vivo Using miRNA-Based Hairpins

Gene Therapy, Dec. 10, 2009; epub ahead of print
Ali et al.


Targeted Forward Mutagenesis by Transitive RNAi

The Plant Journal, Dec. 10, 2009; epub ahead of print
Jorgensen et al.


microRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice

Science, Dec. 11, 2009; 326: 5959, 1549-1554
Olson et al.


miR-122 Over-Expression Contributes to Liver Tumorigenesis

Proceedings of the National Academy of Sciences, Dec. 15, 2009; epub ahead of print
Dejean et al.


Small Interfering RNA Delivery into Murine Bone Marrow-Derived Macrophages Cells by Electroporation

Journal of Immunological Methods, Dec. 16, 2009; epub ahead of print
Jantsch et al.


Relation Between microRNA Expression and Progression and Prognosis of Gastric Cancer: a microRNA Expression Analysis

Lancet Oncology, Dec. 18, 2009; epub ahead of print
Croce et al.


U6 Promoter-Driven siRNA Injection Has Non-Specific Effects in Zebrafish

Biochemical and Biophysical Research Communications, Dec. 21, 2009; epub ahead of print
Jia et al.


RNA Degradation Compromises the Reliability of microRNA Expression Profiling

BMC Biotechnology, Dec. 21, 2009; epub ahead of print
Castoldi et al.


microRNAs miR-1, miR-133a, miR-133b, and miR-208 are Dysregulated in Human Myocardial Infarction

Cardiology, Dec. 21, 2009; epub ahead of print
Glavac et al.


Use of Bacterially Expressed dsRNA to Down-Regulate Entamoeba histolytica Gene Expression

PLoS One, Dec. 23, 2009; 4: 12, e8424
Guillen et al.


Off-Target Analysis of Control siRNA Molecules Reveals Important Differences in the Cytokine Profile and Inflammation Response of Human Fibroblasts

Oligonucleotides, Dec. 28, 2009; epub ahead of print
Rippmann et al.


A Direct Phenotypic Comparison of siRNA Pools and Multiple Individual Duplexes in a Functional Assay

PLoS One, Dec. 29, 2009; 4: 12, e8471
Foley et al.


microRNA and tasiRNA Diversity in Mature Pollen of Arabidopsis thaliana

BMC Genomics, Dec. 30, 2009; epub ahead of print
Dickinson et al.


Anti-Argonaute RIP-Chip Shows That microRNA Transfections Alter Global Patterns of mRNA Recruitment to Microribonucleoprotein Complexes

RNA, Dec. 30, 2009; epub ahead of print
Nelson et al.

The Scan

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.

Analysis of Endogenous Parvoviral Elements Found Within Animal Genomes

Researchers at PLOS Biology have examined the coevolution of endogenous parvoviral elements and animal genomes to gain insight into using the viruses as gene therapy vectors.

Saliva Testing Can Reveal Mosaic CNVs Important in Intellectual Disability

An Australian team has compared the yield of chromosomal microarray testing of both blood and saliva samples for syndromic intellectual disability in the European Journal of Human Genetics.

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.