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Papers of Note: Apr 16, 2009


Retrogradely Transported siRNA Silences Human Mutant SOD1 in Spinal Cord Motor Neurons

Experimental Brain Research, March 4, 2009; epub ahead of print
Islamov et al.

Effective Inhibition of Infectious Bursal Disease Virus Replication by Recombinant Avian Adeno-Associated Virus-Delivered microRNAs

Journal of General Virology, March 4, 2009; epub ahead of print
Xia et al.

Drosophila Argonaute 1 and Argonaute 2 Employ Distinct Mechanism for Translational Repression

Molecular Cell, March 4, 2009; epub ahead of print
Tomari et al.

Transfer of microRNAs by Embryonic Stem-Cell Microvesicles

PLoS One, March 6, 2009; epub ahead of print
Farber et al.

RNA Modulators of Complex Phenotypes in Mammalian Cells

PLoS One, March 9, 2009; epub ahead of print
Arndt et al.

Multiple Dicer Genes in the Early-Diverging Metazoa

Molecular Biology and Evolution, March 10, 2009; epub ahead of print
Schierwater et al.

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Binding of siRNA Molecules is Crucial for RNAi Suppressor Activity of Rice Hoja Blanca Virus NS3 in Plants

Journal of General Virology, March 12, 2009; epub ahead of print
Schnettler et al.

Expression of microRNAs in Cotton

Molecular Biotechnology, March 14, 2009; epub ahead of print
Zhang & Pan

microRNA Expression Profiles Predictive of Human Renal Allograft Status

Proceedings of the National Academy of Sciences, March 16, 2009; epub ahead of print
Suthanthiran et al.

Regulated and Multiple miRNA and siRNA Delivery into Primary Cells by a Lentiviral Platform

Molecular Therapy, March 17, 2009; epub ahead of print
Naldini et al.

Role of 3' UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E — a Computational Inference

PLoS One, March 17, 2009; epub ahead of print
Shapiro et al.

Cell-to-Cell Spread of the RNAi Response Suppresses Semliki Forest Virus Infection of Mosquito Cell Cultures and Cannot Be Antagonized by This Virus

Journal of Virology, March 18, 2009; epub ahead of print
Kohl et al.

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Targeted Systemic Delivery of a Therapeutic siRNA with a Multifunctional Carrier Controls Tumor Proliferation in Mice

Molecular Pharmaceutics, March 18, 2009; epub ahead of print
Lu et al.

Small RNAs and the Control of Transposons and Viruses in Drosophila

Trends in Microbiology
, March 18, 2009; epub ahead of print
van Rij & Berezikov

Dose-Dependent RNAi-Mediated Geminivirus Resistance in the Tropical Root Crop Cassava

Plant Molecular Biology, March 20, 2009; epub ahead of print
Gruissem et al.

Inhibition of Vaccinia Virus Replication by Two siRNAs Targeting B1R and G7L Genes and Their Synergistic Combination with Cidofovir

Antimicrobial Agents and Chemotherapy, March 23, 2009; epub ahead of print
Crance et al.

Evidence of a Tick RNAi Pathway by Comparative Genomics and Reverse Genetics Screen of Targets with Known Loss-of-Function Phenotypes in Drosophila

BMC Molecular Biology, March 26, 2009 epub ahead of print
Bellgard et al.

Profiling RNA Interference-Mediated Toxicity in Neural Cultures for Effective Short Interfering RNA Design

Journal of Gene Medicine, March 26, 2009; epub ahead of print
Logan et al.

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Optimization of Linear Double-Stranded RNA for the Production of Multiple siRNAs Targeting Hepatitis C Virus

RNA, March 26, 2009 epub ahead of print
Kim et al.

Production of Double-Stranded RNA for Interference with TMV Infection Utilizing a Bacterial Prokaryotic Expression System

Applied Microbiology and Biotechnology, March 28, 2009 epub ahead of print
Wen et al.

New Class of microRNA Targets Containing Simultaneous 5'-UTR and 3'-UTR Interaction Sites

Genome Research, March 31, 2009; epub ahead of print
Athey et al.

The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.