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One RNAi-Related Patent Application Published by the US Patent Office


Title: Method of Introducing siRNA into Adipocytes. Number: 20050014264. Filed: Dec. 11, 2003. Lead Inventor: Michael Czech, University of Massachusetts Medical School (CytRx Laboratories).

“In general, it has been difficult to introduce nucleic acid sequences into adipocytes,” the patent application’s abstract states. “Methods are described [in the application] for introducing nucleic acids such as siRNAs into adipocytes, including the introduction of sequences targeting Akt1, Akt2 and Myo1c. Methods for identifying genes involved in glucose transport and for identifying insulin response modulators are described [as are] … therapeutic methods,” the abstract notes.


The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.