Though not defined by any one major breakthrough as in years past, the RNAi therapeutics field made steady progress in 2012, particularly in terms of product and technology development, according to industry insiders.

“2012 was really a year where the field built on the success of 2011 in keying up additional opportunities for clinical applications, and some novel delivery systems” that reflect the growing awareness of the issue of endosomal escape, Jeremy Caldwell, vice president of RNA Therapeutics at Merck, told Gene Silencing News.

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