New Technique for Improved siRNA Delivery, Possible Therapeutic | GenomeWeb

In an effort to take siRNAs from the lab to the clinic, Howard Hughes Medical Institute researcher Steve Dowdy has created a way to improve the delivery of these silencing molecules into cells. His approach, which was published in May in Nature Biotechnology, showed that siRNA could be effectively delivered into three human primary cells by attaching a fusion protein to the molecule. The technique improves upon current methods, which have so far failed to make a successful therapeutic out of RNA interference.

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