While plants and invertebrates have long been known to use RNA interference for viral defense, it was unclear whether mammals did the same. Two new papers published in Science this month, however, reveal that at least some mammalian cells use the gene-silencing mechanisms to fend off viruses.

Although there has been evidence of an RNAi-based anti-viral system in mammals, its existence has been a topic of much debate.

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In Nature this week: factors affecting the success of whole-genome sequencing for routine clinical diagnosis, and more.

A large meta-analysis from an international team reports that nature and nurture have about an equal overall influence on human traits.

The Lasker Foundation's Claire Pomeroy laments the state of NIH funding at Forbes.

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