NEW YORK (GenomeWeb) – A Massachusetts Institute of Technology-led research team this month reported new data suggesting that an siRNA targeting a messenger RNA's 3' untranslated region (UTR), rather than its coding sequence (CDS), can harness the activity of multiple Argonaute proteins to better suppress its target.

As such, RNAi-based therapeutics might benefit from targeting 3' UTRs in order to engage Ago proteins that lack any slicing activity into the target knockdown process, the scientists wrote in their study.

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In Nature this week: association between genome-wide homozygosity and traits like height and cognitive ability, improved CRISPR-Cas9 editing, and more.

A survey examines how age, political leanings, and more influence how Americans view certain scientific topics, the Associated Press reports.

A researcher who pleaded guilty to making false statements in research reports has been sentenced to four and a half years in prison and must pay $7.2 million back to the NIH.

The BabySeq project to study the risks and benefits of sequencing newborns is underway.