NEW YORK (GenomeWeb) – While it has been thought that in general microRNAs only bind to targets that perfectly match their seed regions, newly published data from Thomas Jefferson University researchers suggests that non-canonical binding may be even more widespread.

As such, the miRNA field has potentially been overlooking a significant number of valid miRNA targets as it explores the biological functions of the small, non-coding RNAs, according to Isidore Rigoutsos, director of the Computational Medicine Center at Thomas Jefferson University and senior author of the report.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Register for Free Content
You can still register for access to our free content.

A company hopes to capture the genetic diversity in India to power tailored therapeutics, BBC News reports.

Researchers tie variants in seven genes to insomnia risk, Live Science reports.

The US Environmental Protection Agency has approved an RNAi-based insecticide, according to the Atlantic.

In PLOS this week: locus near OAS1 linked to Sjogren's syndrome, rotavirus reassortment events uncovered by sequencing, and more.