A team led by researchers from Mount Sinai this week reported the discovery that a single microRNA — miR-128 — plays a major role in nerve cell excitability and motor activity by regulating an entire neuronal signaling pathway.

The data, which were generated in mice, also show that inhibition of the miRNA triggered increased motor activity and fatal epilepsy, and that its overexpression attenuated neural responsiveness, suppressed motor activity, and alleviated the movement abnormalities associated with Parkinson's-like disease and seizures.

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In a commentary at eLife, Brandeis University's Eve Marder calls on researchers to value and pursue truth.

Researchers have developed a way to quickly edit white blood cells, according to the New York Times.

In Science this week: rice gene enables plants to grow quickly in times of flooding, and more.

Education-linked genetic variants could also predict a small portion of a person's social mobility, Newsweek reports.

Jul
19
Sponsored by
Thermo Fisher Scientific

This webinar will discuss how ultra-highly sensitive and customizable targeted next-generation sequencing panels are applied in inherited disease research. 

Aug
07
Sponsored by
Qiagen

This webinar will present the results of an evaluation of a web-based variant interpretation software system for clinical next-generation sequencing.